Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.56 |
| ▸ | ITGAV | P06756 | 17/20 | 0.56 |
| ▸ | ITGB6 | P18564 | 8/20 | 0.56 |
| ▸ | ITGB1 | P05556 | 10/20 | 0.54 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.54 |
| ▸ | ITGB5 | P18084 | 7/20 | 0.49 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.49 |
| ▸ | ITGA8 | P53708 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23489508 | 0.92 | ITGB1 (0.61) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL23455311 | 0.92 | ITGB1 (0.61) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL23489345 | 0.91 | ITGB1 (0.55) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL23455402 | 0.91 | ITGB1 (0.55) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL23489611 | 0.88 | ITGB3 (0.57) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL23455495 | 0.85 | ITGB3 (0.60) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL23455492 | 0.85 | ITGB3 (0.60) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL23455514 | 0.83 | ITGB3 (0.56) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL23455516 | 0.83 | ITGB3 (0.56) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL23489362 | 0.79 | ITGB1 (0.69) | ITGB3ITGAVITGB6ITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021119199-A1 | ALPHA-5 BETA-1 INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-06-17 | — | — | WO | disclosed |