Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 14/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 12/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.39 |
| ▸ | ITGAV | P06756 | 7/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.36 |
| ▸ | ITGB8 | P26012 | 3/20 | 0.36 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23518423 | 0.83 | ITGB1 (0.54) | ITGB1ITGA5ITGB3ITGAVITGA4 | |
| SCHEMBL23489245 | 0.81 | ITGB1 (0.57) | ITGB1ITGA5ITGB3ITGAVITGA4 | |
| SCHEMBL23518458 | 0.77 | ITGB1 (0.52) | ITGB1ITGA5ITGB3ITGAVITGA4 | |
| SCHEMBL23489243 | 0.74 | ITGB1 (0.54) | ITGB1ITGA5ITGB3ITGAVITGA4 | |
| SCHEMBL28884201 | 0.73 | ITGB1 (0.62) | ITGB1ITGA5ITGB3ITGAVITGA4 | |
| SCHEMBL23489275 | 0.72 | ITGB1 (0.64) | ITGB1ITGA5ITGB3ITGAVITGA4 | |
| SCHEMBL23455386 | 0.72 | ITGB1 (0.64) | ITGB1ITGA5ITGB3ITGAVITGA4 | |
| SCHEMBL23455360 | 0.71 | ITGB1 (0.57) | ITGB1ITGA5ITGB3ITGAVITGA4 | |
| SCHEMBL23455361 | 0.71 | ITGB1 (0.57) | ITGB1ITGA5ITGB3ITGAVITGA4 | |
| SCHEMBL30000959 | 0.71 | ITGB1 (0.57) | ITGB1ITGA5ITGB3ITGAVITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021119199-A1 | ALPHA-5 BETA-1 INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-06-17 | — | — | WO | disclosed |