Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 13/20 | 0.62 |
| ▸ | ITGA5 | P08648 | 6/20 | 0.62 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 8/20 | 0.42 |
| ▸ | ITGAV | P06756 | 3/20 | 0.42 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.41 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28884248 | 0.95 | ITGB1 (0.57) | ITGB1ITGA5PRMT5WDR77ITGA4 | |
| SCHEMBL28884249 | 0.95 | ITGB1 (0.57) | ITGB1ITGA5PRMT5WDR77ITGA4 | |
| SCHEMBL28884210 | 0.93 | ITGB1 (0.73) | ITGB1ITGA5PRMT5WDR77ITGA4 | |
| SCHEMBL23455521 | 0.92 | ITGB1 (0.53) | ITGB1ITGA5PRMT5WDR77LMNA | |
| SCHEMBL23455519 | 0.92 | ITGB1 (0.53) | ITGB1ITGA5PRMT5WDR77LMNA | |
| SCHEMBL30001345 | 0.92 | ITGB1 (0.53) | ITGB1ITGA5PRMT5WDR77LMNA | |
| SCHEMBL23455349 | 0.89 | ITGB1 (0.61) | ITGB1ITGA5PRMT5WDR77ITGA4 | |
| SCHEMBL23455612 | 0.89 | ITGB1 (0.61) | ITGB1ITGA5PRMT5WDR77ITGA4 | |
| SCHEMBL23455609 | 0.89 | ITGB1 (0.61) | ITGB1ITGA5PRMT5WDR77ITGA4 | |
| SCHEMBL23455347 | 0.89 | ITGB1 (0.61) | ITGB1ITGA5PRMT5WDR77ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115348861-A | Alpha-5 beta-1 inhibitors | 加利福尼亚大学董事会 | 2022-11-15 | — | — | CN | disclosed |