Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17563255 | 0.75 | DPP4 (0.36) | DPP4DPP8ADORA2B | |
| SCHEMBL29669299 | 0.74 | DPP4 (0.35) | DPP4DPP8ADORA2B | |
| SCHEMBL20512424 | 0.74 | DPP4 (0.42) | DPP4DPP8ADORA2B | |
| SCHEMBL24463371 | 0.74 | DPP4 (0.35) | DPP4DPP8ADORA2B | |
| SCHEMBL18911879 | 0.73 | TDO2 (0.31) | — | |
| SCHEMBL18912157 | 0.73 | DYRK1A (0.39) | DPP4 | |
| SCHEMBL17694882 | 0.71 | DPP4 (0.34) | DPP4 | |
| SCHEMBL13676391 | 0.70 | DPP4 (0.38) | DPP4DPP8ADORA2B | |
| SCHEMBL24463141 | 0.69 | DPP4 (0.38) | DPP4DPP8 | |
| SCHEMBL30430122 | 0.69 | DPP4 (0.35) | DPP4DPP8ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210177826-A1 | ANTI-TUMOR EFFECT POTENTIATOR USING NOVEL BIPHENYL COMPOUND | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2021-06-17 | — | — | US | disclosed |
| US-20210179634-A1 | NOVEL BIPHENYL COMPOUND OR SALT THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2021-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210177826-A1 | ANTI-TUMOR EFFECT POTENTIATOR USING NOVEL BIPHENYL COMPOUND | KDM1B, KDM1A, DOT1L | DPP4 3255/4885DPP8 3473/4885ADORA2B 2246/4885 |
| US-20210179634-A1 | NOVEL BIPHENYL COMPOUND OR SALT THEREOF | KDM1B, KDM1A, HDAC1 | DPP4 1929/4885DPP8 2160/4885ADORA2B 4074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.