Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 9/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.37 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18911994 | 0.84 | ADORA2A (0.37) | KDM4ELMNASMN1; SMN2PDK1PDK2 | |
| SCHEMBL23519931 | 0.80 | SYK (0.35) | SYKKCNH2PDK1PDK2ADORA2A | |
| SCHEMBL13106283 | 0.73 | ADORA2A (0.64) | GRM4ADORA2AADORA2B | |
| SCHEMBL18912181 | 0.72 | NR4A2 (0.52) | BAZ2BKDM4E | |
| SCHEMBL2844631 | 0.72 | KDM4E (0.46) | BAZ2BKDM4ESYKKCNH2HTR3A | |
| SCHEMBL21226504 | 0.72 | PDK1 (0.42) | KDM4ELMNAPDK1PDK2ADORA2A | |
| SCHEMBL30599793 | 0.72 | ELANE (0.41) | KDM4ESMN1; SMN2PDK1PDK2 | |
| SCHEMBL22506623 | 0.72 | ELANE (0.41) | KDM4ESMN1; SMN2PDK1PDK2 | |
| SCHEMBL1417391 | 0.71 | KDM4E (0.70) | KDM4EKCNH2HTR3A | |
| SCHEMBL14854483 | 0.71 | BAZ2B (0.41) | BAZ2BKDM4ESYKKCNH2ZAP70 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210177826-A1 | ANTI-TUMOR EFFECT POTENTIATOR USING NOVEL BIPHENYL COMPOUND | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2021-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210177826-A1 | ANTI-TUMOR EFFECT POTENTIATOR USING NOVEL BIPHENYL COMPOUND | KDM1B, KDM1A, DOT1L | BAZ2B 55/4885KDM4E 24/4885SYK 3608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.