Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 12/20 | 0.67 |
| ▸ | CDK2 | P24941 | 7/20 | 0.67 |
| ▸ | CDK1 | P06493 | 5/20 | 0.67 |
| ▸ | CDK4 | P11802 | 1/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.46 |
| ▸ | CDK3 | Q00526 | 3/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.46 |
| ▸ | GSK3A | P49840 | 3/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.44 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23520266 | 0.88 | CDK9 (0.58) | CDK9CDK2CDK1CDK4HDAC3 | |
| SCHEMBL27261178 | 0.87 | CDK9 (0.52) | CDK9CDK2CDK1CDK4HDAC3 | |
| SCHEMBL25082296 | 0.85 | CDK9 (0.73) | CDK9CDK2CDK1CDK4CCNT1 | |
| SCHEMBL30203794 | 0.85 | CDK9 (0.73) | CDK9CDK2CDK1CDK4CCNT1 | |
| SCHEMBL23520419 | 0.84 | CDK9 (0.78) | CDK9CDK2CDK1CDK4CCNT1 | |
| SCHEMBL23520311 | 0.82 | CDK9 (0.90) | CDK9CDK2CDK1CDK4CCNT1 | |
| SCHEMBL25119966 | 0.82 | CDK9 (0.90) | CDK9CDK2CDK1CDK4CCNT1 | |
| SCHEMBL25082294 | 0.81 | CDK9 (0.64) | CDK9CDK2CDK1CDK4HDAC3 | |
| SCHEMBL25082008 | 0.81 | CDK9 (0.69) | CDK9CDK2CDK1CDK4CCNT1 | |
| SCHEMBL30241326 | 0.81 | CDK9 (0.64) | CDK9CDK2CDK1CDK4HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230102081-A1 | COMPOUND AS CYCLIN-DEPENDENT KINASE 9 INHIBITOR AND USE THEREOF | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD. (CN) | 2023-03-30 | — | — | US | disclosed |
| WO-2021115335-A1 | COMPOUND AS CYCLIN-DEPENDENT KINASE 9 INHIBITOR AND USE THEREOF | 石药集团中奇制药技术（石家庄）有限公司 | 2021-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230102081-A1 | COMPOUND AS CYCLIN-DEPENDENT KINASE 9 INHIBITOR AND USE THEREOF | CDK9, CDK4, CDKL4 | CDK9 1/4885CDK2 16/4885CDK1 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.