Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL27782738 | 1.00 | LMNA (0.50) | LMNACA1CA2CA9TSHR | |
| Bicarbonate SCHEMBL33932 | 1.00 | — | — | |
| Bicarbonate SCHEMBL31145089 | 1.00 | LMNA (0.50) | LMNACA1CA2CA9TSHR | |
| Bicarbonate SCHEMBL25188386 | 1.00 | LMNA (0.50) | LMNACA1CA2CA9TSHR | |
| Bicarbonate SCHEMBL17515128 | 0.96 | LMNA (0.47) | LMNACA1CA2CA9TSHR | |
| Bicarbonate SCHEMBL28828250 | 0.96 | — | — | |
| Bicarbonate SCHEMBL31144998 | 0.96 | LMNA (0.47) | LMNACA1CA2CA9TSHR | |
| Bicarbonate SCHEMBL25355622 | 0.96 | — | — | |
| Bicarbonate SCHEMBL21802567 | 0.96 | — | — | |
| Bicarbonate SCHEMBL27972676 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113206297-B | Multifunctional composite electrolyte additive | 徐文忠 | 2022-07-29 | — | — | CN | disclosed |
| EP-3837729-B1 | ELECTROACTIVE MATERIALS FOR METAL-ION BATTERIES | NEXEON LTD (GB) | 2022-06-01 | — | — | EP | disclosed |
| US-20220149349-A1 | Electroactive Materials for Metal-Ion Batteries | NEXEON LIMITED (GB) | 2022-05-12 | — | — | US | disclosed |
| CN-113206297-A | Multifunctional composite electrolyte additive | 徐文忠 | 2021-08-03 | — | — | CN | disclosed |
| EP-3837729-A1 | ELECTROACTIVE MATERIALS FOR METAL-ION BATTERIES | Nexeon Limited (GB) | 2021-06-23 | — | — | EP | disclosed |
| CN-111640917-A | Composite, SiOC structure, method for producing same, negative electrode, composition, and secondary battery | 捷恩智株式会社 | 2020-09-08 | — | — | CN | disclosed |
| CN-106575789-B | Electrolyte formulation | 野猫技术开发公司 | 2020-06-02 | — | — | CN | disclosed |
| CN-110635119-A | Core-shell structure and method for producing same, composition for negative electrode and method for producing same, negative electrode, and secondary battery | 捷恩智株式会社 | 2019-12-31 | — | — | CN | disclosed |