SCHEMBL23522644

SCHEMBL23522644

O=C(CN1CCN(C(=O)c2cccc(-c3nc4ccccc4[nH]3)n2)CC1)c1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LANCL2 Q9NS86 1/20 0.76
HTR2A P28223 2/20 0.43
NPC1 O15118 4/20 0.42
RAB9A P51151 4/20 0.42
HPGD P15428 4/20 0.42
ALDH1A1 P00352 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
KDM4E B2RXH2 2/20 0.42
HTR2B P41595 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
HRH4 Q9H3N8 1/20 0.42
HTR2C P28335 1/20 0.41
ATR Q13535 1/20 0.41
CHRM2 P08172 1/20 0.41
CHRM4 P08173 1/20 0.41
NOS3 P29474 1/20 0.41
NOS1 P29475 1/20 0.41
TP53 P04637 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23561738 0.92 LANCL2 (0.83) LANCL2NPC1RAB9AHPGDALDH1A1
SCHEMBL23561755 0.91 LANCL2 (0.70) LANCL2HTR2ANPC1RAB9AHPGD
SCHEMBL23561754 0.90 LANCL2 (0.73) LANCL2NPC1RAB9AHPGDALDH1A1
SCHEMBL23561740 0.90 LANCL2 (0.67) LANCL2HTR2ANPC1RAB9AHPGD
SCHEMBL23561757 0.90 LANCL2 (0.60) LANCL2HTR2AHPGDALDH1A1KDM4E
SCHEMBL23561758 0.89 LANCL2 (0.70) LANCL2HTR2BMEN1KMT2AHRH4
SCHEMBL23561760 0.88 LANCL2 (0.63) LANCL2HTR2ANPC1RAB9AHPGD
SCHEMBL23561752 0.87 LANCL2 (0.57) LANCL2HTR2ANPC1RAB9AHPGD
Omilancor SCHEMBL17706588 0.87 LANCL2 (1.00) LANCL2NPC1RAB9AHPGDALDH1A1
Omilancor SCHEMBL29349469 0.87 LANCL2 (1.00) LANCL2NPC1RAB9AHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250163017-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME NIMMUNE BIOPHARMA, INC. (US) 2025-05-22 US disclosed
US-12145920-B2 Lanthionine c-like protein 2 ligands, cells prepared therewith, and therapies using same NIMMUNE BIOPHARMA, INC. (US) 2024-11-19 US disclosed
EP-3927427-B1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME NIMMUNE BIOPHARMA INC (US) 2024-02-07 EP disclosed
US-20220274950-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LANDOS BIOPHARMA, INC. (US) 2022-09-01 US disclosed
US-11377437-B2 Lanthionine C-like protein 2 ligands, cells prepared therewith, and therapies using same LANDOS BIOPHARMA, INC. (US) 2022-07-05 US disclosed
US-11377437-B2 Lanthionine C-like protein 2 ligands, cells prepared therewith, and therapies using same LANDOS BIOPHARMA, INC. (US) 2022-07-05 US disclosed
EP-3927427-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LANDOS BIOPHARMA, INC. (US) 2021-12-29 EP disclosed
US-20210355101-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LANDOS BIOPHARMA, INC. (US) 2021-11-18 US disclosed
US-20210355101-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LANDOS BIOPHARMA, INC. (US) 2021-11-18 US disclosed
US-11117881-B2 Lanthionine c-like protein 2 ligands, cells prepared therewith, and therapies using same LANDOS BIOPHARMA, INC. (US) 2021-09-14 US disclosed
US-11117881-B2 Lanthionine c-like protein 2 ligands, cells prepared therewith, and therapies using same LANDOS BIOPHARMA, INC. (US) 2021-09-14 US disclosed
US-20210188800-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LANDOS BIOPHARMA, INC. (US) 2021-06-24 US disclosed
US-20210188800-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LANDOS BIOPHARMA, INC. (US) 2021-06-24 US disclosed
WO-2021127472-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LANDOS BIOPHARMA, INC. (US) 2021-06-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250163017-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LCP2, LANCL2, SSB LANCL2 2/4885HTR2A 3535/4885NPC1 932/4885
US-11377437-B2 Lanthionine C-like protein 2 ligands, cells prepared therewith, and therapies using same LCP2, LANCL2, SSB LANCL2 2/4885HTR2A 3535/4885NPC1 932/4885
US-20210355101-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LCP2, LANCL2, SSB LANCL2 2/4885HTR2A 3535/4885NPC1 932/4885
US-12145920-B2 Lanthionine c-like protein 2 ligands, cells prepared therewith, and therapies using same LCP2, LANCL2, SSB LANCL2 2/4885HTR2A 3535/4885NPC1 932/4885
US-20210188800-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LCP2, LANCL2, SSB LANCL2 2/4885HTR2A 3535/4885NPC1 932/4885
US-11117881-B2 Lanthionine c-like protein 2 ligands, cells prepared therewith, and therapies using same LCP2, LANCL2, SSB LANCL2 2/4885HTR2A 3535/4885NPC1 932/4885
US-20220274950-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LCP2, LANCL2, SSB LANCL2 2/4885HTR2A 3535/4885NPC1 932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.