SCHEMBL23561738

SCHEMBL23561738

O=C(O)CN1CCN(C(=O)c2cccc(-c3nc4ccccc4[nH]3)n2)CC1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LANCL2 Q9NS86 1/20 0.83
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
HRH4 Q9H3N8 1/20 0.45
RAB9A P51151 5/20 0.43
NPC1 O15118 4/20 0.43
HPGD P15428 4/20 0.43
KDM4E B2RXH2 4/20 0.43
ALDH1A1 P00352 3/20 0.43
TP53 P04637 2/20 0.43
HSD17B10 Q99714 2/20 0.43
HTR2B P41595 3/20 0.43
DRD3 P35462 3/20 0.42
DRD2 P14416 2/20 0.42
GRIN2B Q13224 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.40
PKM P14618 2/20 0.40
TSHR P16473 2/20 0.40
LMNA P02545 2/20 0.40
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23522644 0.92 LANCL2 (0.76) LANCL2MEN1KMT2AHRH4RAB9A
Omilancor SCHEMBL29349469 0.91 LANCL2 (1.00) LANCL2MEN1KMT2AHRH4RAB9A
Omilancor SCHEMBL17706588 0.91 LANCL2 (1.00) LANCL2MEN1KMT2AHRH4RAB9A
SCHEMBL25310346 0.88 LANCL2 (0.81) LANCL2MEN1KMT2AHRH4RAB9A
SCHEMBL21043129 0.88 LANCL2 (0.93) LANCL2MEN1KMT2AHRH4RAB9A
SCHEMBL23561755 0.86 LANCL2 (0.70) LANCL2MEN1KMT2AHRH4RAB9A
SCHEMBL23561754 0.86 LANCL2 (0.73) LANCL2MEN1KMT2AHRH4RAB9A
SCHEMBL17705594 0.85 LANCL2 (0.88) LANCL2MEN1KMT2AHRH4RAB9A
SCHEMBL18805072 0.85 LANCL2 (0.88) LANCL2MEN1KMT2AHRH4RAB9A
SCHEMBL23561758 0.84 LANCL2 (0.70) LANCL2MEN1KMT2AHRH4HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11377437-B2 Lanthionine C-like protein 2 ligands, cells prepared therewith, and therapies using same LANDOS BIOPHARMA, INC. (US) 2022-07-05 US disclosed
US-20210355101-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LANDOS BIOPHARMA, INC. (US) 2021-11-18 US disclosed
US-11117881-B2 Lanthionine c-like protein 2 ligands, cells prepared therewith, and therapies using same LANDOS BIOPHARMA, INC. (US) 2021-09-14 US disclosed
US-20210188800-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LANDOS BIOPHARMA, INC. (US) 2021-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11377437-B2 Lanthionine C-like protein 2 ligands, cells prepared therewith, and therapies using same LCP2, LANCL2, SSB LANCL2 2/4885MEN1 1721/4885KMT2A 3376/4885
US-20210355101-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LCP2, LANCL2, SSB LANCL2 2/4885MEN1 1721/4885KMT2A 3376/4885
US-20210188800-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LCP2, LANCL2, SSB LANCL2 2/4885MEN1 1721/4885KMT2A 3376/4885
US-11117881-B2 Lanthionine c-like protein 2 ligands, cells prepared therewith, and therapies using same LCP2, LANCL2, SSB LANCL2 2/4885MEN1 1721/4885KMT2A 3376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.