Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 4/20 | 0.39 |
| ▸ | EIF2AK4 | Q9P2K8 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23522791 | 1.00 | CYP1A2 (0.40) | CYP1A2POLBCYP3A4CYP2C19SCN9A | |
| SCHEMBL23522793 | 1.00 | CYP1A2 (0.40) | CYP1A2POLBCYP3A4CYP2C19SCN9A | |
| SCHEMBL23523253 | 0.83 | HRH3 (0.38) | LIPEEIF2AK4HSD11B1HPGDSMN1; SMN2 | |
| SCHEMBL23523255 | 0.83 | HRH3 (0.38) | LIPEEIF2AK4HSD11B1HPGDSMN1; SMN2 | |
| SCHEMBL23523251 | 0.83 | HRH3 (0.38) | LIPEEIF2AK4HSD11B1HPGDSMN1; SMN2 | |
| SCHEMBL18406192 | 0.82 | LIPE (0.45) | LIPEMAPT | |
| SCHEMBL9105307 | 0.81 | POLB (0.56) | CYP1A2POLBCYP3A4CYP2C19EIF2AK4 | |
| SCHEMBL23523171 | 0.81 | HPGD (0.38) | LIPEEIF2AK4HSD11B1HPGDSMN1; SMN2 | |
| SCHEMBL31664253 | 0.81 | CPT2 (0.47) | LIPEEIF2AK4HPGDSMN1; SMN2MAPT | |
| SCHEMBL30017277 | 0.81 | HPGD (0.38) | LIPEEIF2AK4HSD11B1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11447479-B2 | Compounds active towards nuclear receptors | NUEVOLUTION A/S (DK) | 2022-09-20 | — | — | US | disclosed |
| US-20210188828-A1 | COMPOUNDS ACTIVE TOWARDS NUCLEAR RECEPTORS | NUEVOLUTION A/S (DK) | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188828-A1 | COMPOUNDS ACTIVE TOWARDS NUCLEAR RECEPTORS | NCOA1, NR1H2, NCOA3 | CYP1A2 816/4885POLB 941/4885CYP3A4 621/4885 |
| US-11447479-B2 | Compounds active towards nuclear receptors | NCOA1, NR1H2, NCOA3 | CYP1A2 816/4885POLB 941/4885CYP3A4 621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.