SCHEMBL2352908

SCHEMBL2352908

N#Cc1ccc(Cn2cncc2CN[C@H]2CCN(Cc3cccc(Cl)c3)C2=O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FNTA P49354 18/20 1.00
FNTB P49356 18/20 1.00
PGGT1B P53609 14/20 1.00
KCNH2 Q12809 5/20 1.00
CYP3A4 P08684 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7937545 1.00 FNTA (1.00) FNTAFNTBPGGT1BKCNH2CYP3A4
SCHEMBL2352916 1.00 FNTA (1.00) FNTAFNTBPGGT1BKCNH2CYP3A4
Hydrochloric Acid SCHEMBL7939170 0.99 FNTA (0.98) FNTAFNTBPGGT1BKCNH2CYP3A4
Hydrochloric Acid SCHEMBL7939168 0.99 FNTA (0.98) FNTAFNTBPGGT1BKCNH2CYP3A4
SCHEMBL12991980 0.93 FNTA (0.87) FNTAFNTBPGGT1BKCNH2CYP3A4
SCHEMBL12992215 0.93 FNTA (0.87) FNTAFNTBPGGT1BKCNH2CYP3A4
SCHEMBL12991908 0.92 FNTA (0.88) FNTAFNTBPGGT1BKCNH2CYP3A4
SCHEMBL12991786 0.92 FNTA (0.88) FNTAFNTBPGGT1BKCNH2CYP3A4
SCHEMBL7927571 0.91 FNTA (1.00) FNTAFNTBPGGT1BKCNH2CYP3A4
SCHEMBL7939534 0.91 FNTA (1.00) FNTAFNTBPGGT1BKCNH2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080153758-A1 Compounds Which Inhibits Protein Prenylation E.G. Geranylgeransferse or Farnesyltransferase Inhibitors for Treating Parkinson's Disease EXONHIT THERAPEUTICS SA (FR) 2008-06-26 US claimed
EP-1811984-A1 COMPOUNDS WHICH INHIBITS PROTEIN PRENYLATION E.G. GERANYLGERANYLTRANSFERASE OR FARNESYLTRANSFERASE INHIBITORS FOR TREATING PARKINSON'S DISEASE Exonhit Therapeutics SA (FR) 2007-08-01 EP claimed
WO-2006051423-A1 COMPOUNDS WHICH INHIBITS PROTEIN PRENYLATION E.G. GERANYLGERANYLTRANSFERASE OR FARNESYLTRANSFERASE INHIBITORS FOR TREATING PARKINSON’S DISEASE EXONHIT THERAPEUTICS SA (FR) 2006-05-18 WO claimed
EP-1656931-A1 Compounds which inhibits protein prenylation ( e.g. geranylgeranyltransferase or farnesyltransferase inhibitors) for treating Parkinson's disease Exonhit Therapeutics SA (FR) 2006-05-17 EP claimed
CN-122029269-A Powder supply device 富士胶片株式会社 2026-05-12 CN disclosed
EP-4682240-A1 BIOPROCESS SOLUTION PREPARATION METHOD AND MIXING CONTAINER FUJIFILM Corporation (JP) 2026-01-21 EP disclosed
US-20260002119-A1 METHOD FOR PREPARING BIOPROCESS SOLUTION AND MIXING CONTAINER FUJIFILM CORP (JP) 2026-01-01 US disclosed
US-20250211257-A1 FAST COMBINED CHASE AND GMD DECODING OF GENERALIZED REED-SOLOMON CODES SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-06-26 US disclosed
WO-2025126651-A1 SOLUTION PREPARATION DEVICE, METHOD FOR OPERATING SOLUTION PREPARATION DEVICE, AND PROGRAM FOR OPERATING SOLUTION PREPARATION DEVICE 富士フイルム株式会社 2025-06-19 WO disclosed
WO-2025070314-A1 POWDER SUPPLY DEVICE 富士フイルム株式会社 2025-04-03 WO disclosed
CN-119060579-A Special solvent for photocuring high-fluorine-content transparent coating and preparation method thereof 中昊北方涂料工业研究设计院有限公司 2024-12-03 CN disclosed
WO-2024190822-A1 BIOPROCESS SOLUTION PREPARATION METHOD AND MIXING CONTAINER 富士フイルム株式会社 2024-09-19 WO disclosed
WO-2011088126-A2 TREATMENT OF VIRAL INFECTION WITH PRENYLTRANSFERASE INHIBITORS EIGER BIOPHARMACEUTICALS, INC. (US) 2011-07-21 WO disclosed
US-20080153758-A1 Compounds Which Inhibits Protein Prenylation E.G. Geranylgeransferse or Farnesyltransferase Inhibitors for Treating Parkinson's Disease EXONHIT THERAPEUTICS SA (FR) 2008-06-26 US disclosed
US-20080153758-A1 Compounds Which Inhibits Protein Prenylation E.G. Geranylgeransferse or Farnesyltransferase Inhibitors for Treating Parkinson's Disease EXONHIT THERAPEUTICS SA (FR) 2008-06-26 US disclosed
US-20080153758-A1 Compounds Which Inhibits Protein Prenylation E.G. Geranylgeransferse or Farnesyltransferase Inhibitors for Treating Parkinson's Disease EXONHIT THERAPEUTICS SA (FR) 2008-06-26 US disclosed
EP-1811984-A1 COMPOUNDS WHICH INHIBITS PROTEIN PRENYLATION E.G. GERANYLGERANYLTRANSFERASE OR FARNESYLTRANSFERASE INHIBITORS FOR TREATING PARKINSON'S DISEASE Exonhit Therapeutics SA (FR) 2007-08-01 EP disclosed
WO-2006051423-A1 COMPOUNDS WHICH INHIBITS PROTEIN PRENYLATION E.G. GERANYLGERANYLTRANSFERASE OR FARNESYLTRANSFERASE INHIBITORS FOR TREATING PARKINSON’S DISEASE EXONHIT THERAPEUTICS SA (FR) 2006-05-18 WO disclosed
EP-1656931-A1 Compounds which inhibits protein prenylation ( e.g. geranylgeranyltransferase or farnesyltransferase inhibitors) for treating Parkinson's disease Exonhit Therapeutics SA (FR) 2006-05-17 EP disclosed
WO-2001017992-A1 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 2001-03-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080153758-A1 Compounds Which Inhibits Protein Prenylation E.G. Geranylgeransferse or Farnesyltransferase Inhibitors for Treating Parkinson's Disease FNTA, GGPS1, FNTB FNTA 1/4885FNTB 3/4885PGGT1B 126/4885
US-20260002119-A1 METHOD FOR PREPARING BIOPROCESS SOLUTION AND MIXING CONTAINER SET, BCAS2, BMP2 FNTA 3329/4885FNTB 3242/4885PGGT1B 4489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.