SCHEMBL235327

SCHEMBL235327

CC(C)COC(=O)CC(C)CC(=O)OCC(C)C

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.46
ALDH1A1 P00352 2/20 0.42
PRKCA P17252 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PPARG P37231 1/20 0.35
NCOA2 Q15596 1/20 0.35
NCOA1 Q15788 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
NCOA3 Q9Y6Q9 1/20 0.35
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP3 P08254 1/20 0.34
MMP9 P14780 1/20 0.34
MMP13 P45452 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13863992 0.91 TSHR (0.41) TSHRALDH1A1PRKCATDP1L3MBTL1
SCHEMBL5033123 0.89 PRKCA (0.42) TSHRALDH1A1PRKCATDP1L3MBTL1
SCHEMBL128660 0.87 TSHR (0.48) TSHRALDH1A1PRKCATDP1L3MBTL1
SCHEMBL2500451 0.85 TSHR (0.46) TSHRALDH1A1PRKCATDP1L3MBTL1
SCHEMBL27259225 0.85 TSHR (0.46) TSHRALDH1A1PRKCATDP1L3MBTL1
SCHEMBL27906115 0.85 TSHR (0.39) TSHRALDH1A1PRKCATDP1L3MBTL1
SCHEMBL1456508 0.83 TSHR (0.45) TSHRALDH1A1PRKCATDP1L3MBTL1
SCHEMBL18087555 0.83 TSHR (0.45) TSHRALDH1A1PRKCATDP1L3MBTL1
SCHEMBL9323641 0.83 TSHR (0.50) TSHRALDH1A1PRKCATDP1L3MBTL1
SCHEMBL232470 0.81 TSHR (0.43) TSHRALDH1A1PRKCATDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11186660-B2 Internal electron donor compound for preparing α-olefin polymerization catalyst component YINGKOU XIANGYANG CATALYST CO., LTD. 2021-11-30 US claimed
US-20190218317-A1 INTERNAL ELECTRON DONOR COMPOUND FOR PREPARING ALPHA-OLEFIN POLYMERIZATION CATALYST COMPONENT YINGKOU XIANGYANG CATALYST CO LTD (CN) 2019-07-18 US claimed
US-10287371-B2 Internal electron donor compound for preparing α-olefin polymerization catalyst component YINGKOU XIANGYANG CATALYST CO., LTD. (CN) 2019-05-14 US claimed
CN-103554312-B A kind of internal electron donor compound for preparing alpha-olefin polymerization catalyst component 营口市向阳催化剂有限责任公司 2016-08-17 CN claimed
US-20160229935-A1 Internal Electron Donor Compound for Preparing Alpha-olefin Polymerization Catalyst Component DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2016-08-11 US claimed
CN-103554312-A Internal electron donor compound for preparing alpha-olefin polymerization catalyst component YINGKOU XIANGYANG CATALYST CO LTD 2014-02-05 CN claimed
CN-113179643-B Catalyst component for olefin polymerization 巴塞尔聚烯烃意大利有限公司 2024-07-05 CN disclosed
US-20220081497-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2022-03-17 US disclosed
US-11186660-B2 Internal electron donor compound for preparing α-olefin polymerization catalyst component YINGKOU XIANGYANG CATALYST CO., LTD. 2021-11-30 US disclosed
EP-3908614-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2021-11-17 EP disclosed
CN-113179643-A Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2021-07-27 CN disclosed
WO-2020144035-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2020-07-16 WO disclosed
US-20190218317-A1 INTERNAL ELECTRON DONOR COMPOUND FOR PREPARING ALPHA-OLEFIN POLYMERIZATION CATALYST COMPONENT YINGKOU XIANGYANG CATALYST CO LTD (CN) 2019-07-18 US disclosed
EP-1082359-B1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SRL (IT) 2006-07-19 EP disclosed
CN-1261461-C (Cycloakyl methyl silanes as external donors for polyfin catalysts ENGELHARD CORP (US) 2006-06-28 CN disclosed
CN-1489600-A (Cycloakyl methyl silanes as external donors for polyfin catalysts 恩格哈德公司 2004-04-14 CN disclosed
US-6541582-B1 Catalytic polymerization of propylene via magnesium chloride, titanium chloride, and beta-substituted glutarates; stereospecificity; high isotactic index expressed in terms of high xylene insolubility BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2003-04-01 US disclosed
CN-1306544-A Catalyst and components for olefin polymerization BARSELL TECH CO B V (NL) 2001-08-01 CN disclosed
EP-1082359-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Basell Technology Company B.V. (NL) 2001-03-14 EP disclosed
WO-2000055215-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL TECHNOLOGY COMPANY B.V. (NL) 2000-09-21 WO disclosed