Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | GNAI3 | P08754 | 9/20 | 0.69 |
| ▸ | GNAI1 | P63096 | 9/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.60 |
| ▸ | PPARG | P37231 | 4/20 | 0.48 |
| ▸ | PPARD | Q03181 | 4/20 | 0.48 |
| ▸ | PPARA | Q07869 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29852116 | 1.00 | L3MBTL1 (0.69) | L3MBTL1GNAI3GNAI1TDP1MEN1 | |
| SCHEMBL8972813 | 0.92 | L3MBTL1 (0.80) | L3MBTL1GNAI3GNAI1TDP1MEN1 | |
| SCHEMBL7060548 | 0.92 | L3MBTL1 (0.80) | L3MBTL1GNAI3GNAI1TDP1MEN1 | |
| SCHEMBL1044731 | 0.92 | L3MBTL1 (0.80) | L3MBTL1GNAI3GNAI1TDP1MEN1 | |
| SCHEMBL8972980 | 0.92 | L3MBTL1 (0.80) | L3MBTL1GNAI3GNAI1TDP1MEN1 | |
| SCHEMBL8972823 | 0.92 | L3MBTL1 (0.80) | L3MBTL1GNAI3GNAI1TDP1MEN1 | |
| SCHEMBL4450061 | 0.92 | L3MBTL1 (0.80) | L3MBTL1GNAI3GNAI1TDP1MEN1 | |
| SCHEMBL1045855 | 0.92 | L3MBTL1 (0.80) | L3MBTL1GNAI3GNAI1TDP1MEN1 | |
| SCHEMBL768398 | 0.92 | L3MBTL1 (0.80) | L3MBTL1GNAI3GNAI1TDP1MEN1 | |
| SCHEMBL9415758 | 0.92 | L3MBTL1 (0.80) | L3MBTL1GNAI3GNAI1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230044749-A1 | SELECTIVE CDK 4/6 INHIBITOR CANCER THERAPEUTICS | LUNELLA BIOTECH, INC. (CA) | 2023-02-09 | — | — | US | disclosed |
| US-20230043357-A1 | SELECTIVE CDK4/6 INHIBITOR CANCER THERAPEUTICS | LUNELLA BIOTECH, INC. (CA) | 2023-02-09 | — | — | US | disclosed |
| WO-2021124106-A1 | SELECTIVE CDK4/6 INHIBITOR CANCER THERAPEUTICS | LUNELLA BIOTECH, INC. (CA) | 2021-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230044749-A1 | SELECTIVE CDK 4/6 INHIBITOR CANCER THERAPEUTICS | CDK6, CDK4, CDKL4 | L3MBTL1 1236/4885GNAI3 1890/4885GNAI1 1998/4885 |
| US-20230043357-A1 | SELECTIVE CDK4/6 INHIBITOR CANCER THERAPEUTICS | CDK4, CDK6, CDKL4 | L3MBTL1 2212/4885GNAI3 2096/4885GNAI1 1917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.