SCHEMBL23533337

SCHEMBL23533337

CCCCCC(COS(=O)(=O)c1ccc(C)cc1)COS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 1/20 0.42
PLA2G2C Q5R387 1/20 0.42
CA12 O43570 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
ALDH1A1 P00352 5/20 0.39
CYP2C9 P11712 2/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C19 P33261 1/20 0.39
NR1I2 O75469 1/20 0.38
LMNA P02545 1/20 0.38
ALB P02768 1/20 0.38
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
STAT3 P40763 2/20 0.37
PRSS1 P07477 1/20 0.37
PRSS2 P07478 1/20 0.37
PRSS3 P35030 1/20 0.37
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26479527 0.95 MCHR1 (0.44) MCHR1PLA2G2CCA12CA2CA9
SCHEMBL3680210 0.95 MCHR1 (0.44) MCHR1PLA2G2CCA12CA2CA9
SCHEMBL1770004 0.95 MCHR1 (0.44) MCHR1PLA2G2CCA12CA2CA9
SCHEMBL13608639 0.95 MCHR1 (0.44) MCHR1PLA2G2CCA12CA2CA9
SCHEMBL4298010 0.95 CA12 (0.42) MCHR1PLA2G2CCA12CA2CA9
SCHEMBL20561114 0.94 MCHR1 (0.43) MCHR1PLA2G2CCA12CA2CA9
SCHEMBL27813828 0.94 PRSS1 (0.44) MCHR1PLA2G2CCA12CA2CA9
SCHEMBL3416137 0.93 PRSS1 (0.46) MCHR1PLA2G2CCA12CA2CA9
SCHEMBL2476440 0.90 ALDH1A1 (0.43) MCHR1PLA2G2CCA12CA2CA9
SCHEMBL4290352 0.89 CA12 (0.47) PLA2G2CCA12CA2CA9SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4076649-A1 CYCLOALKYL-CONTAINING CARBOXYLIC ACIDS AND USES THEREOF Liminal Biosciences Limited (GB) 2022-10-26 EP disclosed
WO-2021124272-A1 CYCLOALKYL-CONTAINING CARBOXYLIC ACIDS AND USES THEREOF Liminal Biosciences Limited (GB) 2021-06-24 WO disclosed