Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | DHODH | Q02127 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 9/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | TOP1 | P11387 | 2/20 | 0.52 |
| ▸ | TOP2A | P11388 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23534618 | 0.92 | RAB9A (0.55) | RAB9ATP53L3MBTL1DHODHNPC1 | |
| SCHEMBL23534176 | 0.91 | NPC1 (0.61) | RAB9ADHODHNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL23534022 | 0.89 | NPC1 (0.63) | RAB9ATP53DHODHNPC1SMN1; SMN2 | |
| SCHEMBL23534181 | 0.88 | HSD17B10 (0.64) | RAB9ATP53L3MBTL1DHODHNPC1 | |
| SCHEMBL23534172 | 0.88 | RAB9A (0.52) | RAB9ATP53L3MBTL1DHODHNPC1 | |
| SCHEMBL23534135 | 0.86 | RAB9A (0.50) | RAB9ATP53L3MBTL1DHODHNPC1 | |
| SCHEMBL23534529 | 0.83 | NPC1 (0.60) | RAB9ANPC1SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL23535830 | 0.82 | NPC1 (0.62) | RAB9ATP53DHODHNPC1SMN1; SMN2 | |
| SCHEMBL23534200 | 0.81 | MAPT (0.67) | RAB9ATP53NPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL23534156 | 0.80 | MAPT (0.58) | RAB9ANPC1SMN1; SMN2ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021126118-A1 | SYNTHESIS OF 2-(SUBSTITUTEDPHENYL)-5-(SUBSTITUTEDHETEROARYL)- 1H-BENZIMIDAZOLE DERIVATIVES AND INVESTIGATION OF THEIR BIOLOGICAL EFFECTS | ANADOLU ÜNİVERSİTESİ (TR) | 2021-06-24 | — | — | WO | disclosed |