SCHEMBL23534205

SCHEMBL23534205

COC(C)(C)CCc1ccc(O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.50
ESR2 Q92731 2/20 0.50
CALM1 P0DP23 1/20 0.48
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
SPHK2 Q9NRA0 1/20 0.45
CA2 P00918 1/20 0.45
TMEM97 Q5BJF2 1/20 0.44
SIGMAR1 Q99720 1/20 0.44
ALDH1A1 P00352 3/20 0.43
ADRA2A P08913 3/20 0.43
SLC6A2 P23975 3/20 0.43
KDM4E B2RXH2 2/20 0.43
HTR1A P08908 1/20 0.43
CYP2C19 P33261 1/20 0.43
HTR3A P46098 1/20 0.43
BACE1 P56817 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ADORA3 P0DMS8 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1835580 0.79 ESR1 (0.61) ESR1ESR2CALM1KMT2AMEN1
SCHEMBL19509051 0.79 ALDH1A1 (0.41) SPHK2ALDH1A1SLC6A2TAAR1LMNA
SCHEMBL16114597 0.79 ESR1 (0.59) ESR1ESR2CALM1KMT2AMEN1
SCHEMBL2600042 0.79 ESR1 (0.60) ESR1ESR2CALM1KMT2AMEN1
SCHEMBL7627333 0.77 ESR1 (0.46) ESR1ESR2CALM1KMT2AMEN1
SCHEMBL7253631 0.77 ESR1 (0.56) ESR1ESR2KMT2AMEN1CA2
SCHEMBL10318595 0.77 SPHK2 (0.40) SPHK2CA2TMEM97ALDH1A1LMNA
SCHEMBL27537745 0.77 BLM (0.44) ESR1ESR2CALM1KMT2AMEN1
SCHEMBL29109681 0.75 ESR1 (0.54) ESR1ESR2CALM1KMT2AMEN1
SCHEMBL11134725 0.75 ESR1 (0.54) ESR1ESR2CALM1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021125418-A1 PHENOLIC COMPOUND, SKIN-WHITENING COSMETIC COMPOSITION COMPRISING SAME, AND SKIN-WHITENING COSMETIC PRODUCT (주)셀인바이오 2021-06-24 WO disclosed