SCHEMBL235348

SCHEMBL235348

[CH]1CCOCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL872370 1.00
SCHEMBL975303 0.81
SCHEMBL6567371 0.79
SCHEMBL974504 0.73
SCHEMBL3898003 0.69
SCHEMBL2127024 0.69
SCHEMBL9958468 0.69
SCHEMBL9957680 0.69 ALDH1A1 (0.39)
SCHEMBL76137 0.65
SCHEMBL57118 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112437772-B Bcl-2 inhibitors 百济神州有限公司 2023-11-21 CN claimed
CN-116802179-A BCL-2 inhibitors 百济神州有限公司 2023-09-22 CN claimed
US-20230159522-A1 BCL-2 INHIBITOR BEONE MEDICINES I GMBH (CH) 2023-05-25 US claimed
EP-4136084-A1 BCL-2 INHIBITOR BeiGene, Ltd. (KY) 2023-02-22 EP claimed
US-20230002369-A1 Bcl-2 INHIBITORS BEONE MEDICINES I GMBH (CH) 2023-01-05 US claimed
US-20220402915-A1 BCL-2 INHIBITORS BEONE MEDICINES I GMBH (CH) 2022-12-22 US claimed
CN-114929689-A Bcl-2 inhibitors 百济神州有限公司 2022-08-19 CN claimed
WO-2021208963-A1 BCL-2 INHIBITOR BEIGENE, LTD. (KY) 2021-10-21 WO claimed
WO-2021083135-A1 Bcl-2 INHIBITORS BEIGENE, LTD. (KY) 2021-05-06 WO claimed
EP-3788042-A1 BCL-2 INHIBITORS BeiGene, Ltd. (KY) 2021-03-10 EP claimed
EP-1082322-B1 OXAZOLIDINONE DERIVATIVES AS ANTIBIOTIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ASTRAZENECA AB (SE) 2004-01-28 EP claimed
EP-1357122-A2 Oxazolidinone compounds and pharmaceutical compositions containing them AstraZeneca AB (SE) 2003-10-29 EP claimed
US-20030144263-A1 Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them SYNGENTA LIMITED (GB) 2003-07-31 US claimed
EP-0892799-B1 QUINAZOLINE DERIVATIVES ASTRAZENECA AB (SE) 2001-08-22 EP claimed
EP-0892799-A1 QUINAZOLINE DERIVATIVES ZENECA LIMITED (GB) 1999-01-27 EP claimed
US-H1759-H NEW HERBICIDE MOLECULAR COMPRISING A RING SELECT FROM THE GROUP OF PYRIMIDINE, TRIAZOLE, PYRAZOLE, ISOINDOLE, THIADIAZOLO(3,4-A)PYRIDAZINE, TRIAZINE(1,2,4), INDAZOLE, TETRAZOLE, TRIAZOLE(4,3-A)PYRIDINE FMC CORPORATION (US) 1998-11-03 US claimed
US-5770603-A ANTICARCINOGENIC AGENTS ZENECA LIMITED (GB) 1998-06-23 US claimed
WO-1997038994-A1 QUINAZOLINE DERIVATIVES ZENECA LIMITED (GB) 1997-10-23 WO claimed
WO-1997032879-A1 7-ALKYL-PYRROLO[2,3-d]PYRIMIDINES NOVARTIS AG (CH) 1997-09-12 WO claimed
US-5658942-A Octahydronaphthalene oxime compounds for cholesterol synthesis inhibition SANKYO COMPANY, LIMITED (JP) 1997-08-19 US claimed