Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | HTR2B | P41595 | 4/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.39 |
| ▸ | PARP1 | P09874 | 4/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23535339 | 0.82 | PARP10 (0.41) | HTR2CHTR2BCRBNPARP1KMT2A | |
| SCHEMBL29791265 | 0.72 | CRBN (0.73) | CRBNDDB1 | |
| SCHEMBL22873420 | 0.72 | CRBN (0.73) | CRBNDDB1 | |
| SCHEMBL29502600 | 0.70 | CRBN (0.46) | HTR2CCRBNPARP1MAPT | |
| SCHEMBL21997911 | 0.70 | CRBN (0.55) | HTR2CHTR2BCRBNPARP1DDB1 | |
| SCHEMBL4345609 | 0.69 | CRBN (0.56) | HTR2CHTR2BCRBNPARP1DDB1 | |
| SCHEMBL14996499 | 0.65 | PARP1 (0.57) | HTR2CPARP1SRD5A1HTTPARP2 | |
| SCHEMBL25656352 | 0.65 | PARP10 (0.52) | PARP1SRD5A1 | |
| SCHEMBL11956536 | 0.64 | PARP1 (0.47) | HTR2CPARP1POLBHTTPARP2 | |
| SCHEMBL29502372 | 0.64 | CRBN (0.47) | CRBNPARP1DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021126973-A1 | COMPOUNDS MODULATING PROTEIN RECRUITMENT AND/OR DEGRADATION | ORIONIS BIOSCIENCES, INC. (US) | 2021-06-24 | — | — | WO | disclosed |