SCHEMBL23535554

SCHEMBL23535554

Fc1cccc(-c2ccc3ncc(-c4ccccc4)n3n2)c1

nearest known ligand 0.83

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FYN P06241 20/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL102704 0.94 FYN (0.87) FYN
SCHEMBL18613547 0.91 FYN (1.00) FYN
SCHEMBL30521832 0.88 FYN (1.00) FYN
SCHEMBL18613907 0.88 FYN (1.00) FYN
SCHEMBL18613339 0.87 FYN (1.00) FYN
SCHEMBL22131031 0.85 FYN (1.00) FYN
SCHEMBL103055 0.85 FYN (0.85) FYN
SCHEMBL30006704 0.83 FYN (0.72) FYN
SCHEMBL23535567 0.83 FYN (0.72) FYN
SCHEMBL18613725 0.82 FYN (1.00) FYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120025336-A LIN28 inhibitors and methods of use thereof 加利福尼亚大学董事会 2025-05-23 CN disclosed
CN-115087657-B LIN28 inhibitors and methods of use thereof 加利福尼亚大学董事会 2025-01-21 CN disclosed
US-20230059009-A1 INHIBITORS OF LIN28 AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-02-23 US disclosed
US-20230059009-A1 INHIBITORS OF LIN28 AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-02-23 US disclosed
EP-4077332-A1 INHIBITORS OF LIN28 AND METHODS OF USE THEREOF The Regents of the University of California (US) 2022-10-26 EP disclosed
CN-115087657-A LIN28 inhibitor and method of use thereof 加利福尼亚大学董事会 2022-09-20 CN disclosed
WO-2021126779-A1 INHIBITORS OF LIN28 AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-06-24 WO disclosed
WO-2021126779-A1 INHIBITORS OF LIN28 AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-06-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230059009-A1 INHIBITORS OF LIN28 AND METHODS OF USE THEREOF LIN28A, DDX21, BMI1 FYN 3592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.