Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 0.67 |
| ▸ | ADK | P55263 | 4/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29931964 | 1.00 | GSK3B (0.67) | GSK3BADKL3MBTL1MEN1KMT2A | |
| SCHEMBL7117167 | 0.76 | GSK3B (0.61) | GSK3BADKL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7467559 | 0.71 | TSHR (0.58) | GSK3BADKL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18619418 | 0.69 | GSK3B (0.53) | GSK3BADKL3MBTL1F10TSHR | |
| SCHEMBL7116601 | 0.69 | F10 (0.69) | GSK3BADKMEN1KMT2AF10 | |
| SCHEMBL7123884 | 0.69 | F10 (0.64) | GSK3BADKL3MBTL1F10MAPT | |
| SCHEMBL27143122 | 0.68 | CMA1 (0.47) | GSK3BMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8554715 | 0.67 | L3MBTL1 (1.00) | GSK3BADKL3MBTL1MEN1KMT2A | |
| SCHEMBL7115355 | 0.66 | F10 (0.64) | GSK3BADKL3MBTL1ALDH1A1F10 | |
| SCHEMBL7117172 | 0.66 | F10 (0.64) | GSK3BADKL3MBTL1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087440-A | TRPML modulators | 卡斯玛治疗公司 | 2022-09-20 | — | — | CN | disclosed |
| WO-2021127337-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |
| WO-2021127337-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |