Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23537921 | 0.83 | MAPT (0.51) | MAPTLMNAHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL23538144 | 0.81 | MAPT (0.63) | MAPTLMNAHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL2991924 | 0.80 | MAPT (0.51) | MAPTLMNAHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL23537751 | 0.78 | HPGD (0.49) | MAPTLMNAHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL27097014 | 0.78 | MAPT (0.51) | MAPTLMNAHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL27096888 | 0.77 | MAPT (0.48) | MAPTLMNAHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL27096922 | 0.76 | MAPT (0.49) | MAPTLMNAHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL27096956 | 0.75 | MAPT (0.48) | MAPTLMNAHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL13844986 | 0.74 | HTT (0.50) | MAPTLMNAHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL6816187 | 0.74 | MAPT (0.79) | MAPTLMNAHPGDKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127397-A1 | NITROGEN HETEROCYCLIC COMPOUNDS AND METHODS OF USE | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |