Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23538009 | 0.81 | HPGD (0.40) | HPGDALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL13844986 | 0.80 | HTT (0.50) | HPGDALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL23537705 | 0.79 | L3MBTL1 (0.51) | HPGDALDH1A1RAB9AMAPTTSHR | |
| SCHEMBL23537985 | 0.78 | MAPT (0.49) | HPGDALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL2986980 | 0.77 | EGFR (0.44) | HPGDALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL30729947 | 0.75 | MRGPRX4 (0.40) | HPGDALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL23538135 | 0.75 | RAB9A (0.53) | HPGDALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL27097024 | 0.75 | MRGPRX4 (0.40) | HPGDALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL3727149 | 0.74 | ALDH1A1 (0.58) | HPGDALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL30729931 | 0.74 | HTR2A (0.52) | ALDH1A1RAB9AMAPTNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127397-A1 | NITROGEN HETEROCYCLIC COMPOUNDS AND METHODS OF USE | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |