Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28558027 | 0.95 | ALDH1A1 (0.50) | TSHRALDH1A1MAPK1TP53CYP3A4 | |
| Oxalic Acid SCHEMBL28735102 | 0.92 | TSHR (0.52) | TSHRALDH1A1MAPK1TP53CYP3A4 | |
| Hydrogen Peroxide SCHEMBL27921718 | 0.92 | TSHR (0.62) | TSHRALDH1A1MAPK1TP53CYP3A4 | |
| Acetic Acid SCHEMBL28845095 | 0.90 | ALDH1A1 (0.53) | TSHRALDH1A1MAPK1TP53CYP3A4 | |
| Carbamic Acid SCHEMBL27463719 | 0.90 | TSHR (0.50) | TSHRALDH1A1MAPK1TP53CYP3A4 | |
| 1,4-Butanediol SCHEMBL17603250 | 0.89 | TSHR (0.50) | TSHRALDH1A1MAPK1TP53CYP3A4 | |
| Succinic Acid SCHEMBL27818706 | 0.88 | TSHR (0.48) | TSHRALDH1A1MAPK1TP53CYP3A4 | |
| Malonic Acid SCHEMBL27324468 | 0.88 | TSHR (0.48) | TSHRALDH1A1MAPK1TP53CYP3A4 | |
| SCHEMBL2596956 | 0.88 | TSHR (0.48) | TSHRALDH1A1MAPK1TP53CYP3A4 | |
| Acetone SCHEMBL18343602 | 0.87 | ALDH1A1 (0.55) | TSHRALDH1A1MAPK1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112701346-B | Solid electrolyte contact surface conditioning material and mixed electrolyte system thereof | 辉能科技股份有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-114940808-B | Recyclable epoxy resin Vitrimer material and preparation method thereof | 湖北瀚飞新材料科技有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-117186762-A | Flame-retardant UV-oxygen dual-curing polyurethane acrylate three-proofing paint | 上海惠涂化工科技有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-112786969-B | Lithium battery structure and electrode layer structure thereof | 辉能科技股份有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-114940808-A | Recyclable epoxy resin Vitrimer material and preparation method thereof | 湖北瀚飞新材料科技有限公司 | 2022-08-26 | — | — | CN | claimed |
| CN-105440255-B | Artificial resin-fixing system based on cyclic carbonate resins, production and use thereof | 费希尔厂有限责任两合公司 | 2020-04-21 | — | — | CN | claimed |
| EP-2998334-B1 | CURABLE RESIN WITH SIGNIFICANT LEVELS OF CYCLIC CARBONATE GROUPS, AND CYCLOCARBONATE RESIN BASED FIXING SYSTEMS, THEIR PREPARATION AND USE | FISCHERWERKE GMBH & CO KG (DE) | 2020-03-25 | — | — | EP | claimed |
| US-20160083501-A1 | HARDENABLE SYNTHETIC RESIN COMPRISING CONSIDERABLE PROPORTIONS OF CYCLIC CARBONATE GROUPS, AS WELL AS/AND CYCLOCARBONATE-RESIN-BASED FIXING SYSTEMS, THE PRODUCTION AND USE THEREOF | FISCHERWERKE GMBH & CO. KG (DE) | 2016-03-24 | — | — | US | claimed |
| EP-2998334-A1 | CURABLE RESIN WITH SIGNIFICANT LEVELS OF CYCLIC CARBONATE GROUPS, AND CYCLOCARBONATE RESIN BASED FIXING SYSTEMS, THEIR PREPARATION AND USE | fischerwerke GmbH & Co. KG (DE) | 2016-03-23 | — | — | EP | claimed |
| EP-1896550-B1 | STABILIZED ELECTROCHROMIC MEDIA | BASF SE (DE) | 2013-08-14 | — | — | EP | claimed |
| US-7595011-B2 | One or more solvents, one or more materials which are functional elements of electrochromic devices, one or more ultraviolet light absorbers selected from hydroxyphenylbenzotriazoles and tris-aryl-s-triazines, and one or more NH or N-alkyl hindered amine light stabilizers; discoloration inhibition | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-09-29 | — | — | US | claimed |
| CN-100520551-C | Electrochromic medium composition, preparation method thereof and electroactive device comprising same | CIBA SC HOLDING AG (CH) | 2009-07-29 | — | — | CN | claimed |
| CN-101377599-A | Electrochromism reflecting device | FENG CHINA UNIVERSITY (CN) | 2009-03-04 | — | — | CN | claimed |
| EP-1896550-A1 | STABILIZED ELECTROCHROMIC MEDIA | Ciba Specialty Chemicals Holding Inc. (CH) | 2008-03-12 | — | — | EP | claimed |
| CN-1985214-A | Stable electrochromic medium | CIBA SC HOLDING AG (CH) | 2007-06-20 | — | — | CN | claimed |
| EP-1789842-A1 | STABILIZED ELECTROCHROMIC MEDIA | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-05-30 | — | — | EP | claimed |
| WO-2007003508-A1 | STABILIZED ELECTROCHROMIC MEDIA | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-01-11 | — | — | WO | claimed |
| US-20070002423-A1 | Stabilized electrochromic media | CIBA SPECIALTY CHEMICALS CORP. | 2007-01-04 | — | — | US | claimed |
| WO-2006005691-A1 | STABILIZED ELECTROCHROMIC MEDIA | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-01-19 | — | — | WO | claimed |
| US-20060007519-A1 | Stabilized electrochromic media | CIBA SPECIALTY CHEMICALS CORP. | 2006-01-12 | — | — | US | claimed |