Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377122 | 0.89 | ABCB1 (0.59) | ABCB1 | |
| SCHEMBL2949349 | 0.89 | ABCB1 (0.59) | ABCB1 | |
| SCHEMBL377244 | 0.89 | ABCB1 (0.59) | ABCB1 | |
| SCHEMBL13467902 | 0.81 | ABCB1 (0.48) | ABCB1 | |
| SCHEMBL13236579 | 0.81 | ABCB1 (0.52) | ABCB1 | |
| SCHEMBL13236578 | 0.81 | ABCB1 (0.52) | ABCB1 | |
| SCHEMBL2353865 | 0.79 | ABCB1 (0.47) | ABCB1 | |
| SCHEMBL13236553 | 0.77 | ABCB1 (0.48) | ABCB1 | |
| SCHEMBL1719195 | 0.76 | KDM4E (0.62) | — | |
| SCHEMBL14146432 | 0.73 | ABCB1 (0.43) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349328-A1 | METHODS FOR THE TREATMENT OF CANCER | LUDWIG INSTITUTE FOR CANCER RESEARCH (US) | 2011-08-03 | — | — | EP | claimed |
| EP-2349328-A1 | METHODS FOR THE TREATMENT OF CANCER | LUDWIG INSTITUTE FOR CANCER RESEARCH (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2009140549-A1 | COMBINATIONS VEGF(R) INHIBITORS AND HEPATOCYTE GROWTH FACTOR (C-MET) INHIBITORS FOR THE TREATMENT OF CANCER | AMGEN INC. (US) | 2009-11-19 | — | — | WO | disclosed |