Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.56 |
| ▸ | WDR5 | P61964 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20703534 | 0.82 | MAPT (0.65) | MYCWDR5MAPTALDH1A1MEN1 | |
| SCHEMBL3793669 | 0.80 | PKM (0.58) | MYCWDR5MAPTALDH1A1MEN1 | |
| SCHEMBL1641146 | 0.80 | MYC (0.52) | MYCWDR5MAPTALDH1A1MEN1 | |
| SCHEMBL49097 | 0.78 | AURKA (0.57) | MYCWDR5MAPTALDH1A1MEN1 | |
| SCHEMBL11326282 | 0.78 | MYC (0.65) | MYCWDR5MAPTALDH1A1MEN1 | |
| Bromide SCHEMBL7143173 | 0.77 | MYC (0.61) | MYCWDR5MAPTALDH1A1MEN1 | |
| SCHEMBL23539555 | 0.76 | MYC (0.53) | MYCWDR5MAPTALDH1A1MEN1 | |
| SCHEMBL1641715 | 0.73 | MYC (0.52) | MYCWDR5MAPTALDH1A1MEN1 | |
| SCHEMBL1145909 | 0.72 | HSP90AA1 (0.71) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30818066 | 0.71 | MAPT (1.00) | MYCWDR5MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127301-A1 | 4-PHENYL-N-(PHENYL)THIAZOL-2-AMINE DERIVATIVES AND RELATED COMPOUNDS AS ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS FOR THE TREATMENT OF E.G. ANGIOGENESIS IMPLICATED OR INFLAMMATORY DISORDERS | Ikena Oncology, Inc. (US) | 2021-06-24 | — | — | WO | disclosed |