Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 6/20 | 0.38 |
| ▸ | CES2 | O00748 | 5/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL29097133 | 0.93 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| Ethylene Glycol SCHEMBL27490784 | 0.90 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL29398848 | 0.89 | TSHR (0.46) | ALDH1A1SMN1; SMN2LMNATSHRCES1 | |
| SCHEMBL16432 | 0.89 | TSHR (0.46) | ALDH1A1SMN1; SMN2LMNATSHRCES1 | |
| Butyl Alcohol SCHEMBL7693245 | 0.88 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL1230281 | 0.86 | TSHR (0.43) | ALDH1A1SMN1; SMN2LMNATSHRCES1 | |
| SCHEMBL10557096 | 0.86 | TSHR (0.43) | ALDH1A1SMN1; SMN2LMNATSHRCES1 | |
| SCHEMBL2997424 | 0.86 | TSHR (0.43) | ALDH1A1SMN1; SMN2LMNATSHRCES1 | |
| SCHEMBL1230019 | 0.86 | TSHR (0.43) | ALDH1A1SMN1; SMN2LMNATSHRCES1 | |
| SCHEMBL848566 | 0.86 | TSHR (0.43) | ALDH1A1SMN1; SMN2LMNATSHRCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351872-B1 | TREATMENT METHOD USING PLASMA | MIYAHARA HIDEKAZU (JP) | 2021-06-09 | — | — | EP | disclosed |
| US-10020502-B2 | Positive active material for rechargeable lithium battery, method of preparing same, and rechargeable lithium battery including same | SAMSUNG SDI CO., LTD. (KR) | 2018-07-10 | — | — | US | disclosed |
| US-20160149215-A1 | POSITIVE ACTIVE MATERIAL FOR RECHARGEABLE LITHIUM BATTERY, METHOD OF PREPARING SAME, AND RECHARGEABLE LITHIUM BATTERY INCLUDING SAME | SAMSUNG SDI CO., LTD. (KR) | 2016-05-26 | — | — | US | disclosed |
| CN-104014375-A | Macromolecule inorganic composite nanosphere supported Ni-B catalyst and preparation method and application thereof | UNIV SHAOXING | 2014-09-03 | — | — | CN | disclosed |
| US-20110236593-A1 | Treatment Method Using Plasma | OKINO AKITOSHI | 2011-09-29 | — | — | US | disclosed |
| EP-2351872-A1 | TREATMENT METHOD USING PLASMA | Tokyo Institute of Technology (JP) | 2011-08-03 | — | — | EP | disclosed |