Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 0.77 |
| ▸ | PTAFR | P25105 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17542518 | 0.87 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL23542859 | 0.86 | MAPK14 (0.78) | MAPK14 | |
| SCHEMBL23542850 | 0.78 | MAPK14 (0.82) | MAPK14 | |
| SCHEMBL19367817 | 0.78 | MAPK14 (0.79) | MAPK14 | |
| SCHEMBL17542505 | 0.77 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL19367800 | 0.76 | MAPK14 (0.80) | MAPK14 | |
| SCHEMBL17542578 | 0.75 | MAPK14 (0.82) | MAPK14 | |
| SCHEMBL17552066 | 0.75 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL23542852 | 0.73 | MAPK14 (0.75) | MAPK14 | |
| SCHEMBL23542834 | 0.70 | MAPK14 (0.71) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3186245-B1 | MAPK INHIBITORS | EverBrilliant Pharma Pty Ltd (AU) | 2021-06-23 | — | — | EP | disclosed |