Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.47 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 7/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16134193 | 0.95 | STK17B (0.51) | STK17BSTK17AMEN1KMT2AGAA | |
| SCHEMBL24331900 | 0.89 | STK17B (0.46) | STK17BSTK17AMEN1KMT2AGAA | |
| SCHEMBL31436060 | 0.87 | STK17B (0.58) | STK17BSTK17AMEN1KMT2AGAA | |
| SCHEMBL31436080 | 0.81 | TDP1 (0.58) | STK17BSTK17AMEN1KMT2AGAA | |
| SCHEMBL31436112 | 0.81 | TDP1 (0.62) | STK17BSTK17AMEN1KMT2AGAA | |
| SCHEMBL31436059 | 0.80 | STK17B (0.62) | STK17BSTK17AMEN1KMT2AGAA | |
| SCHEMBL31436071 | 0.80 | TDP1 (0.69) | STK17BSTK17AMEN1KMT2AGAA | |
| SCHEMBL31436057 | 0.79 | STK17B (0.48) | STK17BSTK17AMEN1KMT2AGAA | |
| SCHEMBL17564597 | 0.78 | LMNA (0.51) | STK17BSTK17AMEN1KMT2AGAA | |
| SCHEMBL31436097 | 0.78 | STK17B (0.50) | STK17BSTK17AMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3143037-B1 | ALPHA4BETA7 INTEGRIN THIOETHER PEPTIDE ANTAGONISTS | PROTAGONIST THERAPEUTICS INC (US) | 2021-06-23 | — | — | EP | disclosed |