⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27620689 | 0.74 | TSHR (0.30) | — | |
| SCHEMBL992721 | 0.72 | — | — | |
| SCHEMBL5334154 | 0.61 | — | — | |
| SCHEMBL28863422 | 0.61 | — | — | |
| SCHEMBL10535005 | 0.59 | — | — | |
| SCHEMBL28688969 | 0.59 | — | — | |
| SCHEMBL28683358 | 0.59 | — | — | |
| SCHEMBL7540249 | 0.59 | ALDH1A1 (0.33) | — | |
| SCHEMBL8275609 | 0.59 | TSHR (0.38) | — | |
| SCHEMBL1078047 | 0.59 | TSHR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560982-A2 | PHOSPHORAMIDITES FOR SYNTHETIC RNA IN THE REVERSE DIRECTION | Chemgenes Corporation (US) | 2013-02-27 | — | — | EP | disclosed |
| WO-2011103468-A2 | PHOSPHORAMIDITES FOR SYNTHETIC RNA IN THE REVERSE DIRECTION | CHEMGENES CORPORATION (US) | 2011-08-25 | — | — | WO | disclosed |