Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.36 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2355219 | 1.00 | HCAR2 (0.45) | HCAR2KEAP1NFE2L2POLBPOLA1 | |
| SCHEMBL2354333 | 1.00 | HCAR2 (0.45) | HCAR2KEAP1NFE2L2POLBPOLA1 | |
| SCHEMBL2354518 | 1.00 | HCAR2 (0.45) | HCAR2KEAP1NFE2L2POLBPOLA1 | |
| SCHEMBL2354511 | 1.00 | HCAR2 (0.45) | HCAR2KEAP1NFE2L2POLBPOLA1 | |
| SCHEMBL2353221 | 0.93 | HCAR2 (0.48) | HCAR2KEAP1NFE2L2POLBPOLA1 | |
| SCHEMBL2353228 | 0.93 | HCAR2 (0.48) | HCAR2KEAP1NFE2L2POLBPOLA1 | |
| SCHEMBL2356403 | 0.83 | HCAR2 (0.63) | HCAR2ATMEPHX1MAPTRAB9A | |
| SCHEMBL2356398 | 0.83 | HCAR2 (0.63) | HCAR2ATMEPHX1MAPTRAB9A | |
| SCHEMBL2353799 | 0.83 | HCAR2 (0.63) | HCAR2ATMEPHX1MAPTRAB9A | |
| SCHEMBL6685300 | 0.83 | HCAR2 (0.63) | HCAR2ATMEPHX1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092143-A1 | ANTIFOULING COMPOSITION | JOTUN A/S (NO) | 2011-08-04 | — | — | WO | disclosed |