SCHEMBL2353221

SCHEMBL2353221

CCCC[SiH2]OC(=O)/C=C/C(=O)OC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 6/20 0.48
KEAP1 Q14145 1/20 0.48
NFE2L2 Q16236 1/20 0.48
ATM Q13315 1/20 0.42
MAPT P10636 2/20 0.37
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
POLB P06746 1/20 0.35
POLA1 P09884 1/20 0.35
GFPT1 Q06210 1/20 0.33
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
EPHX1 P07099 1/20 0.32
ZDHHC20 Q5W0Z9 2/20 0.32
ZDHHC2 Q9UIJ5 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2353228 1.00 HCAR2 (0.48) HCAR2KEAP1NFE2L2ATMMAPT
SCHEMBL2355219 0.93 HCAR2 (0.45) HCAR2KEAP1NFE2L2ATMMAPT
SCHEMBL2354518 0.93 HCAR2 (0.45) HCAR2KEAP1NFE2L2ATMMAPT
SCHEMBL2354341 0.93 HCAR2 (0.45) HCAR2KEAP1NFE2L2ATMMAPT
SCHEMBL2354511 0.93 HCAR2 (0.45) HCAR2KEAP1NFE2L2ATMMAPT
SCHEMBL2354333 0.93 HCAR2 (0.45) HCAR2KEAP1NFE2L2ATMMAPT
SCHEMBL6421786 0.82 ATM (0.69) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL6421793 0.82 ATM (0.69) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL6554239 0.79 ATM (0.38) HCAR2ATMHPGDTSHRALDH1A1
SCHEMBL6554268 0.77 ATM (0.36) HCAR2ATMMAPTPOLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011092143-A1 ANTIFOULING COMPOSITION JOTUN A/S (NO) 2011-08-04 WO disclosed