Phenol

Phenol

SCHEMBL2354353

Oc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl.Oc1ccccc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.38
CYP1A2 P05177 2/20 0.35
CYP1A1 P04798 1/20 0.35
CYP19A1 P11511 1/20 0.35
ACLY P53396 2/20 0.35
LMNA P02545 1/20 0.34
PTGS1 P23219 1/20 0.34
SLC6A2 P23975 1/20 0.34
CYP2C19 P33261 1/20 0.34
PTGS2 P35354 1/20 0.34
SLC6A3 Q01959 1/20 0.34
HIF1A Q16665 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
MAOB P27338 3/20 0.34
PTPN1 P18031 2/20 0.34
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
GLA P06280 1/20 0.33
CA3 P07451 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2166615 0.89 HTT (0.41) HTTCYP1A2LMNAPTGS1SLC6A2
SCHEMBL8408601 0.79 KDM4E (0.41) CYP1A2CYP1A1CYP19A1LMNAPTGS1
SCHEMBL7979193 0.78 HTT (0.37) HTT
SCHEMBL7075218 0.78 HTT (0.40) HTTCYP1A2PTGS1CYP2C19PTGS2
SCHEMBL8405762 0.78 HTT (0.37) HTT
SCHEMBL8657700 0.77 HTT (0.40) HTTNPC1RAB9A
SCHEMBL8520882 0.76 HTT (0.53) HTTLMNACYP2C19MAOB
SCHEMBL8407828 0.76 HTT (0.41) HTTCYP1A2CYP2C19MAOB
SCHEMBL8344201 0.76 HSD17B10 (0.35) HTTCYP1A2CYP2C19HIF1A
SCHEMBL8344199 0.76 HSD17B10 (0.35) HTTCYP1A2CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2039671-B1 PROCESS FOR PRODUCTION OF ALCOHOL COMPOUND SUMITOMO CHEMICAL CO (JP) 2011-08-31 EP claimed