Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | SCN1A | P35498 | 2/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1818116 | 0.82 | SCN1A (0.49) | CHRM3SCN1ASCN2ASCN3AMEN1 | |
| SCHEMBL697519 | 0.80 | — | — | |
| SCHEMBL1078014 | 0.80 | EPHX1 (0.39) | CHRM3MEN1KMT2ACHRM4CHRM5 | |
| SCHEMBL16845009 | 0.77 | SMN1; SMN2 (0.47) | CHRM3MEN1KMT2ACHRM4CHRM5 | |
| SCHEMBL19504740 | 0.77 | ATM (0.42) | CHRM3SCN1ASCN2ASCN3AMEN1 | |
| SCHEMBL698655 | 0.76 | — | — | |
| SCHEMBL10344338 | 0.76 | EPHX1 (0.45) | RAB9AEPHX1 | |
| SCHEMBL305953 | 0.76 | EPHX1 (0.50) | RAB9AEPHX1 | |
| SCHEMBL16845011 | 0.74 | CHRM4 (0.50) | CHRM3SCN1ASCN2ASCN3AMEN1 | |
| SCHEMBL10025768 | 0.74 | EPHX2 (0.39) | CYP1A2HIF1AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534147-A1 | SPIROHETEROCYCLICAL SUBSTITUTED TETRAMIC ACID DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011098443-A1 | SPIROHETEROCYCLICAL SUBSTITUTED TETRAMIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-08-18 | — | — | WO | disclosed |