Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 17/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20611271 | 0.87 | CNR2 (0.57) | CNR2AKT1CACNA2D1SMPD3 | |
| SCHEMBL20998150 | 0.83 | CNR2 (0.47) | CNR2AKT1CACNA2D1SMPD3 | |
| SCHEMBL20611081 | 0.83 | CNR2 (0.47) | CNR2AKT1CACNA2D1SMPD3 | |
| SCHEMBL20611153 | 0.82 | CNR2 (0.49) | CNR2AKT1CACNA2D1SMPD3 | |
| SCHEMBL20611000 | 0.81 | CNR2 (0.68) | CNR2 | |
| SCHEMBL23544240 | 0.80 | CNR2 (0.66) | CNR2AKT1CACNA2D1 | |
| SCHEMBL16555056 | 0.76 | CNR2 (0.60) | CNR2AKT1CACNA2D1 | |
| SCHEMBL16555061 | 0.76 | CNR2 (0.60) | CNR2AKT1CACNA2D1 | |
| SCHEMBL23544260 | 0.76 | CNR2 (0.63) | CNR2AKT1CACNA2D1SMPD3 | |
| SCHEMBL20998151 | 0.74 | HRH4 (0.39) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3483163-B1 | TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES AS CB2 RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2021-06-23 | — | — | EP | disclosed |