SCHEMBL2354445

SCHEMBL2354445

CCCNc1nc(NCCC)nc(SC)n1

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.48
CYP2C19 P33261 2/20 0.48
KMT2A Q03164 3/20 0.46
LMNA P02545 3/20 0.43
MEN1 O00255 1/20 0.43
NR1I2 O75469 1/20 0.41
AHR P35869 1/20 0.41
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
CA9 Q16790 3/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
HTT P42858 1/20 0.38
PKM P14618 1/20 0.37
RAD52 P43351 1/20 0.37
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
KCNH3 Q9ULD8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2697123 0.94 CYP1A2 (0.58) CYP1A2CYP2C19KMT2ALMNAMEN1
SCHEMBL11808006 0.92 LMNA (0.46) CYP1A2CYP2C19KMT2ALMNAMEN1
SCHEMBL17576127 0.91 CYP1A2 (0.42) CYP1A2CYP2C19KMT2ALMNAMEN1
SCHEMBL7764235 0.88 KMT2A (0.66) CYP1A2CYP2C19KMT2ALMNAMEN1
SCHEMBL17576131 0.87 KMT2A (0.56) CYP1A2CYP2C19KMT2ALMNAMEN1
SCHEMBL8077062 0.84 KMT2A (0.54) CYP1A2CYP2C19KMT2AHTTCYP3A4
SCHEMBL10543159 0.83 CYP1A2 (0.61) CYP1A2CYP2C19KMT2ALMNAMEN1
SCHEMBL9490786 0.83 CYP1A2 (0.46) CYP1A2CYP2C19KMT2ALMNACA1
SCHEMBL10899963 0.82 KMT2A (0.43) CYP1A2CYP2C19KMT2ALMNAMEN1
Simetryn SCHEMBL8409672 0.82 LMNA (0.54) CYP1A2CYP2C19KMT2ALMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2359692-A1 Herbicidal compositions ISAGRO S.p.A. (IT) 2011-08-24 EP disclosed
US-3988292-A A TRIAZINE DERIVATIVE TEIJIN LIMITED (JA) 1976-10-26 US disclosed