Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 5/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3734185 | 0.82 | ANO1 (0.51) | ANO1IDO1GAASMN1; SMN2HPGD | |
| SCHEMBL23086057 | 0.79 | ALOX15 (0.46) | PCSK9SERPINE1SMN1; SMN2HPGDMEN1 | |
| SCHEMBL27207487 | 0.78 | PPARA (0.51) | CTSLGAAHPGDALDH1A1KDM4E | |
| SCHEMBL27203760 | 0.78 | PPARA (0.51) | CTSLGAAHPGDALDH1A1KDM4E | |
| SCHEMBL30825606 | 0.77 | KLK5 (0.47) | IDO1CTSLGAASMN1; SMN2HPGD | |
| SCHEMBL248758 | 0.74 | GAA (0.48) | ANO1IDO1GAASMN1; SMN2HPGD | |
| SCHEMBL18052209 | 0.74 | PCSK9 (0.48) | PCSK9CTSLHPGDHTTMEN1 | |
| SCHEMBL14047146 | 0.74 | PCSK9 (0.48) | PCSK9CTSL | |
| SCHEMBL30079765 | 0.74 | IDO1 (0.52) | ANO1IDO1GAASMN1; SMN2HPGD | |
| SCHEMBL20446470 | 0.74 | IDO1 (0.52) | ANO1IDO1GAASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3250549-B1 | CYCLOPROPYLMETHANAMINES AS SELECTIVE 5-HT(2C) RECEPTOR AGONISTS | UNIV ILLINOIS (US) | 2021-06-23 | — | — | EP | disclosed |