Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WIZ | O95785 | 6/20 | 0.72 |
| ▸ | IKZF2 | Q9UKS7 | 11/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.46 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.46 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24760626 | 1.00 | WIZ (0.72) | WIZIKZF2CRBNIKZF3IKZF1 | |
| SCHEMBL23533113 | 0.94 | WIZ (0.80) | WIZIKZF2CRBNIKZF3IKZF1 | |
| SCHEMBL23533111 | 0.94 | WIZ (0.80) | WIZIKZF2CRBNIKZF3IKZF1 | |
| SCHEMBL23533166 | 0.94 | WIZ (0.80) | WIZIKZF2CRBNIKZF3IKZF1 | |
| SCHEMBL23533112 | 0.91 | WIZ (0.74) | WIZIKZF2CRBNIKZF3IKZF1 | |
| SCHEMBL23533115 | 0.91 | WIZ (0.74) | WIZIKZF2CRBNIKZF3IKZF1 | |
| SCHEMBL23532774 | 0.91 | WIZ (0.76) | WIZIKZF2CRBNIKZF3IKZF1 | |
| SCHEMBL23532771 | 0.91 | WIZ (0.76) | WIZIKZF2CRBNIKZF3IKZF1 | |
| SCHEMBL23532940 | 0.90 | WIZ (0.88) | WIZIKZF2CRBNIKZF3IKZF1 | |
| SCHEMBL23532936 | 0.90 | WIZ (0.88) | WIZIKZF2CRBNIKZF3IKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114828959-B | 3- (5-methoxy-1-oxo-isoindolin-2-yl) piperidine-2, 6-dione derivative and application thereof | 诺华股份有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-114828959-A | 3- (5-methoxy-1-oxoisoindolin-2-yl) piperidine-2, 6-dione derivatives and uses thereof | 诺华股份有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-114828959-B | 3- (5-methoxy-1-oxo-isoindolin-2-yl) piperidine-2, 6-dione derivative and application thereof | 诺华股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-114828959-A | 3- (5-methoxy-1-oxoisoindolin-2-yl) piperidine-2, 6-dione derivatives and uses thereof | 诺华股份有限公司 | 2022-07-29 | — | — | CN | disclosed |
| WO-2021124172-A1 | 3-(5-METHOXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2021-06-24 | — | — | WO | disclosed |