Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 14/20 | 0.55 |
| ▸ | CDK9 | P50750 | 3/20 | 0.55 |
| ▸ | CDK1 | P06493 | 3/20 | 0.51 |
| ▸ | CLK1 | P49759 | 4/20 | 0.49 |
| ▸ | CLK2 | P49760 | 4/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 10/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | CCNE2 | O96020 | 7/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 7/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 7/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30911090 | 1.00 | CDK2 (0.55) | CDK2CDK9CDK1CLK1CLK2 | |
| SCHEMBL26772811 | 0.91 | CDK2 (0.61) | CDK2CDK9CDK1CCNE1CCNB1 | |
| SCHEMBL31072409 | 0.87 | CDK2 (0.54) | CDK2CDK9CDK1CLK1CLK2 | |
| SCHEMBL23547494 | 0.81 | CDK1 (0.53) | CDK2CDK9CDK1CLK1CLK2 | |
| SCHEMBL23529877 | 0.81 | CDK2 (0.45) | CDK2CDK9CDK1CLK1CLK2 | |
| SCHEMBL23547543 | 0.81 | CTSL (0.46) | CDK2CDK9CDK1 | |
| SCHEMBL31707903 | 0.80 | CLK1 (0.56) | CDK2CDK9CDK1CLK1CLK2 | |
| SCHEMBL23530130 | 0.80 | CLK1 (0.46) | CDK2CDK9CDK1CLK1CLK2 | |
| SCHEMBL23547377 | 0.80 | CDK2 (0.44) | CDK2CDK9CDK1CLK1CLK2 | |
| SCHEMBL23547332 | 0.80 | CDK2 (0.48) | CDK2CDK9CDK1CLK1CLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021121390-A1 | HETEROCYCLIC COMPOUND, AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, INTERMEDIATE THEREOF AND APPLICATION THEREOF | 苏州信诺维医药科技股份有限公司 | 2021-06-24 | — | — | WO | disclosed |