Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 13/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23571246 | 1.00 | CALCRL (0.40) | CALCRLTACR1LIPGCCR2CCR5 | |
| SCHEMBL23571238 | 1.00 | CALCRL (0.40) | CALCRLTACR1LIPGCCR2CCR5 | |
| SCHEMBL15578246 | 0.86 | CALCRL (0.41) | CALCRLLIPGFPR2 | |
| SCHEMBL12228953 | 0.86 | FPR2 (0.36) | TACR1CCR2CCR5FPR2KDM4E | |
| SCHEMBL23571247 | 0.85 | CALCRL (0.39) | CALCRLLIPGFPR2 | |
| SCHEMBL23570674 | 0.84 | CALCRL (0.39) | CALCRLTACR1 | |
| SCHEMBL23571256 | 0.84 | CALCRL (0.39) | CALCRLTACR1 | |
| SCHEMBL23570702 | 0.84 | CALCRL (0.39) | CALCRL | |
| SCHEMBL23547576 | 0.84 | CALCRL (0.39) | CALCRL | |
| SCHEMBL23547608 | 0.84 | CALCRL (0.39) | CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022263573-A1 | ISOXAZOLINE PESTICIDES | ELANCO TIERGESUNDHEIT AG (US) | 2022-12-22 | — | — | WO | disclosed |
| WO-2021127188-A1 | ISOXAZOLINE DERIVATIVES AS PESTICIDES | ELANCO TIERGESUNDHEIT AG (CH) | 2021-06-24 | — | — | WO | disclosed |