Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.71 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.71 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.65 |
| ▸ | PI4KA | P42356 | 2/20 | 0.65 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.65 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.65 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.65 |
| ▸ | DPP4 | P27487 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.65 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.65 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.65 |
| ▸ | GAPDH | P04406 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.65 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.65 |
| ▸ | STAT6 | P42226 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29502688 | 1.00 | EGFR (0.71) | EGFRERBB2ADORA3ADORA1PI4KA | |
| SCHEMBL23547973 | 1.00 | EGFR (0.71) | EGFRERBB2ADORA3ADORA1PI4KA | |
| SCHEMBL20870832 | 0.91 | ADORA3 (0.67) | EGFRERBB2ADORA3ADORA1PI4KA | |
| SCHEMBL8621803 | 0.91 | ADORA3 (0.67) | EGFRERBB2ADORA3ADORA1PI4KA | |
| SCHEMBL8672670 | 0.91 | ADORA3 (0.67) | EGFRERBB2ADORA3ADORA1PI4KA | |
| SCHEMBL24264134 | 0.89 | ADORA3 (0.62) | EGFRERBB2ADORA3ADORA1PI4KA | |
| SCHEMBL24538798 | 0.89 | ADORA3 (0.75) | EGFRERBB2ADORA3ADORA1PI4KA | |
| SCHEMBL12150808 | 0.89 | ADORA3 (0.75) | EGFRERBB2ADORA3ADORA1PI4KA | |
| SCHEMBL12031049 | 0.89 | ADORA3 (0.72) | EGFRERBB2ADORA3ADORA1PI4KA | |
| SCHEMBL23050294 | 0.89 | ADORA3 (0.75) | EGFRERBB2ADORA3ADORA1PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210189392-A1 | S-ANTIGEN TRANSPORT INHIBITING OLIGONUCLEOTIDE POLYMERS AND METHODS | ALIGOS THERAPEUTICS, INC. | 2021-06-24 | — | — | US | disclosed |