Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 12/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | FPR2 | P25090 | 5/20 | 0.43 |
| ▸ | FPR3 | P25089 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14227252 | 1.00 | FASN (0.54) | FASNIDO1TDO2GPR119FPR2 | |
| SCHEMBL2301640 | 0.87 | FASN (0.57) | FASNIDO1TDO2FPR2 | |
| SCHEMBL2301635 | 0.87 | FASN (0.57) | FASNIDO1TDO2FPR2 | |
| SCHEMBL2354954 | 0.86 | FASN (0.59) | FASN | |
| SCHEMBL2355150 | 0.86 | FASN (0.58) | FASNIDO1TDO2GPR119 | |
| SCHEMBL14151928 | 0.85 | FASN (0.59) | FASN | |
| SCHEMBL2358609 | 0.84 | FASN (0.60) | FASN | |
| SCHEMBL2358613 | 0.84 | FASN (0.60) | FASN | |
| SCHEMBL2356717 | 0.83 | FASN (0.57) | FASN | |
| SCHEMBL2356722 | 0.83 | FASN (0.57) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102858175-A | Triazolones as fatty acid synthase inhibitors | GLAXOSMITHKLINE LLC | 2013-01-02 | — | — | CN | disclosed |
| WO-2011103546-A1 | TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-08-25 | — | — | WO | disclosed |