Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 11/20 | 0.58 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2356328 | 0.88 | FASN (0.66) | FASNUSP30GPR119 | |
| SCHEMBL14152133 | 0.87 | FASN (0.59) | FASN | |
| SCHEMBL2356363 | 0.86 | FASN (0.79) | FASNGPR119 | |
| SCHEMBL2298684 | 0.86 | FASN (0.61) | FASN | |
| SCHEMBL2298682 | 0.86 | FASN (0.61) | FASN | |
| SCHEMBL14227252 | 0.86 | FASN (0.54) | FASNIDO1TDO2GPR119 | |
| SCHEMBL2355087 | 0.86 | FASN (0.54) | FASNIDO1TDO2GPR119 | |
| SCHEMBL2354565 | 0.85 | FASN (0.58) | FASN | |
| SCHEMBL2355232 | 0.85 | FASN (0.72) | FASN | |
| SCHEMBL2355947 | 0.84 | FASN (0.60) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102858175-A | Triazolones as fatty acid synthase inhibitors | GLAXOSMITHKLINE LLC | 2013-01-02 | — | — | CN | disclosed |
| WO-2011103546-A1 | TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-08-25 | — | — | WO | disclosed |