Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 7/20 | 0.50 |
| ▸ | RARA | P10276 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
| ▸ | RARG | P13631 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19784752 | 0.86 | F2RL3 (0.79) | F2RL3KDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL145188 | 0.85 | F2RL3 (0.55) | F2RL3KDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL27512690 | 0.83 | F2RL3 (0.80) | F2RL3KDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL363569 | 0.82 | F2RL3 (1.00) | F2RL3KDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL29403731 | 0.82 | F2RL3 (1.00) | F2RL3KDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL14869422 | 0.79 | PKN1 (0.51) | F2RL3KDM4EHPGDALDH1A1NAMPT | |
| SCHEMBL4478363 | 0.79 | F2RL3 (0.74) | F2RL3KDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL6705737 | 0.78 | ELANE (0.70) | KDM4ERXFP1ELANE | |
| Acetic Acid SCHEMBL15622681 | 0.76 | KMT2A (0.57) | KDM4EHPGDALDH1A1SMN1; SMN2NAMPT | |
| SCHEMBL6352575 | 0.74 | KDM4E (0.59) | F2RL3KDM4EHPGDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210188877-A1 | TRICYCLIC HETEROARYL-SUBSTITUTED QUINOLINE AND AZAQUINOLINE COMPOUNDS AS PAR4 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188877-A1 | TRICYCLIC HETEROARYL-SUBSTITUTED QUINOLINE AND AZAQUINOLINE COMPOUNDS AS PAR4 INHIBITORS | F2RL3, PARP14, F2R | F2RL3 1/4885KDM4E 1720/4885HPGD 1301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.