SCHEMBL2355245

SCHEMBL2355245

CCCCCOC(=O)c1ccccc1C(=O)OCC(CC)CCCC

nearest known ligand 0.86

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.86
CYP3A4 P08684 5/20 0.86
CA2 P00918 1/20 0.86
PRSS1 P07477 1/20 0.82
PRSS2 P07478 1/20 0.82
PRSS3 P35030 1/20 0.82
LMNA P02545 5/20 0.74
TSHR P16473 8/20 0.70
MAPK1 P28482 4/20 0.70
TP53 P04637 1/20 0.70
TDP1 Q9NUW8 3/20 0.63
L3MBTL1 Q9Y468 3/20 0.63
HSD17B10 Q99714 3/20 0.57
KDM4E B2RXH2 2/20 0.57
POLB P06746 1/20 0.57
ATM Q13315 1/20 0.49
MAPT P10636 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28117954 0.99 PRSS1 (0.85) ALDH1A1CYP3A4CA2PRSS1PRSS2
SCHEMBL27964979 0.99 PRSS1 (0.85) ALDH1A1CYP3A4CA2PRSS1PRSS2
SCHEMBL28117899 0.99 PRSS1 (0.85) ALDH1A1CYP3A4CA2PRSS1PRSS2
SCHEMBL2351535 0.99 PRSS1 (0.85) ALDH1A1CYP3A4CA2PRSS1PRSS2
Bis(2-Ethylhexyl) Phthalate SCHEMBL8498138 0.99 PRSS1 (0.85) ALDH1A1CYP3A4CA2PRSS1PRSS2
Bis(2-Ethylhexyl) Phthalate SCHEMBL6245567 0.99 PRSS1 (0.85) ALDH1A1CYP3A4CA2PRSS1PRSS2
SCHEMBL30801429 0.99 PRSS1 (0.85) ALDH1A1CYP3A4CA2PRSS1PRSS2
SCHEMBL29662788 0.99 PRSS1 (0.85) ALDH1A1CYP3A4CA2PRSS1PRSS2
Bis(2-Ethylhexyl) Phthalate SCHEMBL9473452 0.99 PRSS1 (0.85) ALDH1A1CYP3A4CA2PRSS1PRSS2
Bis(2-Ethylhexyl) Phthalate SCHEMBL10605171 0.96 ALDH1A1 (0.89) ALDH1A1CYP3A4CA2PRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2636688-B1 METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, AND OLEFIN POLYMERS TOHO TITANIUM CO LTD (JP) 2016-11-16 EP disclosed
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
CN-103764690-A Process for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin polymer TOHO TITANIUM CO LTD 2014-04-30 CN disclosed
EP-2636688-A1 METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, AND OLEFIN POLYMERS Toho Titanium Co., Ltd. (JP) 2013-09-11 EP disclosed
CN-103087222-A Olefin polymerization catalyst, process for producing olefin polymer, polypropylene resin composition and article comprising the same SUMITOMO CHEMICAL CO 2013-05-08 CN disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
EP-2360190-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME Toho Titanium CO., LTD. (JP) 2011-08-24 EP disclosed