Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10313015 | 0.84 | HTR2C (0.42) | HTR2CHTR2B | |
| SCHEMBL16217182 | 0.84 | CYP3A4 (0.41) | HTR2CHTR2B | |
| SCHEMBL23530081 | 0.81 | CCR1 (0.42) | HTR2CHTR2B | |
| SCHEMBL20738524 | 0.80 | HTR2A (0.44) | HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL31014049 | 0.79 | KDM4E (0.30) | — | |
| SCHEMBL30101526 | 0.74 | HTR2C (0.36) | HTR2CHTR2BKCNH2 | |
| SCHEMBL17984826 | 0.74 | HTR2C (0.36) | HTR2CHTR2BKCNH2 | |
| SCHEMBL6859088 | 0.71 | ADRA2A (0.43) | HTR2C | |
| SCHEMBL15961568 | 0.71 | ADRA2A (0.40) | HTR2C | |
| SCHEMBL22169253 | 0.69 | ADRA2A (0.34) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021121294-A1 | TRIAZOLOPYRIDAZINE DERIVATIVE, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 上海赛默罗生物科技有限公司 | 2021-06-24 | — | — | WO | disclosed |