Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | PKM | P14618 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 3/20 | 0.40 |
| ▸ | SNCA | P37840 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL540756 | 0.84 | PTGS2 (0.47) | HSD17B10ALOX15CYP2C9ALOX12CYP2C19 | |
| SCHEMBL6213448 | 0.75 | BACE1 (0.44) | HSD17B10ALOX15CYP2C9ALOX12CYP2C19 | |
| SCHEMBL6262789 | 0.75 | BACE1 (0.46) | HSD17B10ALOX15CYP2C9ALOX12CYP2C19 | |
| SCHEMBL4728425 | 0.75 | BACE1 (0.46) | HSD17B10ALOX15CYP2C9ALOX12CYP2C19 | |
| SCHEMBL14392073 | 0.75 | BACE1 (0.46) | HSD17B10ALOX15CYP2C9ALOX12CYP2C19 | |
| SCHEMBL6262620 | 0.75 | BACE1 (0.46) | HSD17B10ALOX15CYP2C9ALOX12CYP2C19 | |
| SCHEMBL6262786 | 0.75 | BACE1 (0.46) | HSD17B10ALOX15CYP2C9ALOX12CYP2C19 | |
| SCHEMBL20169853 | 0.75 | BACE1 (0.46) | HSD17B10ALOX15CYP2C9ALOX12CYP2C19 | |
| SCHEMBL1578287 | 0.74 | BACE1 (0.43) | HSD17B10ALOX15CYP2C9ALOX12CYP2C19 | |
| SCHEMBL809418 | 0.74 | BACE1 (0.43) | HSD17B10ALOX15CYP2C9ALOX12CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004168-B1 | STABLE ORAL PHARMACEUTICAL COMPOSITION CONTAINING THYROID HORMONE RECEPTOR AGONISTS | KAROBIO AB (SE) | 2011-08-03 | — | — | EP | disclosed |