Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343719 | 1.00 | DPP4 (0.46) | DPP4DPP7HDAC1HDAC8DPP9 | |
| SCHEMBL343718 | 1.00 | DPP4 (0.46) | DPP4DPP7HDAC1HDAC8DPP9 | |
| SCHEMBL29362057 | 1.00 | DPP4 (0.46) | DPP4DPP7HDAC1HDAC8DPP9 | |
| SCHEMBL7140778 | 0.81 | DPP4 (0.52) | DPP4DPP7 | |
| SCHEMBL10022727 | 0.81 | DPP4 (0.52) | DPP4DPP7 | |
| SCHEMBL1552897 | 0.81 | HTR2A (0.35) | DPP4 | |
| SCHEMBL1552901 | 0.81 | HTR2A (0.35) | DPP4 | |
| SCHEMBL1552994 | 0.79 | MEN1 (0.38) | DPP4DPP9 | |
| SCHEMBL1552997 | 0.79 | MEN1 (0.38) | DPP4DPP9 | |
| SCHEMBL20630900 | 0.78 | DPP4 (0.52) | DPP4DPP7DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011102640-A2 | METHOD FOR PREPARING SITAGLIPTIN AND AMINE SALT INTERMEDIATES USED THEREIN | HANMI HOLDINGS CO., LTD. (KR) | 2011-08-25 | — | — | WO | disclosed |