Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10022727 | 1.00 | DPP4 (0.52) | DPP4DPP7KCNH2 | |
| SCHEMBL21503614 | 0.83 | DPP4 (0.57) | DPP4KCNH2 | |
| SCHEMBL343719 | 0.81 | DPP4 (0.46) | DPP4DPP7 | |
| SCHEMBL29362057 | 0.81 | DPP4 (0.46) | DPP4DPP7 | |
| SCHEMBL2355496 | 0.81 | DPP4 (0.46) | DPP4DPP7 | |
| SCHEMBL343718 | 0.81 | DPP4 (0.46) | DPP4DPP7 | |
| SCHEMBL9987227 | 0.80 | DPP4 (0.59) | DPP4DPP7 | |
| SCHEMBL20630900 | 0.79 | DPP4 (0.52) | DPP4DPP7 | |
| SCHEMBL10586294 | 0.78 | IDO1 (0.44) | DPP4DPP7 | |
| SCHEMBL13193427 | 0.77 | DPP4 (0.50) | DPP4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999045008-A1 | 3-[4-(4-CYANOPHENYL)THIAZOL-2-Y)]-1-(1H-1,2,4-TRIAZOL-1-YL)-BUTAN-2-OL DERIVATIVES HAVING ANTIFUNGAL ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 1999-09-10 | — | — | WO | claimed |
| EP-1280795-A2 | N-SUBSTITUTED CARBAMOYLOXYALKYL-AZOLIUM DERIVATIVES | Basilea Pharmaceutica AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| WO-2001032652-A2 | N-SUBSTITUTED CARBAMOYLOXYALKYL-AZOLIUM DERIVATIVES | BASILEA PHARMACEUTICA AG (CH) | 2001-05-10 | — | — | WO | disclosed |