Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 11/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 1/20 | 0.40 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2355672 | 0.92 | EGLN1 (0.54) | EGLN1ALDH1A1MAPTL3MBTL1TEAD4 | |
| SCHEMBL2204759 | 0.86 | ALDH1A1 (0.53) | EGLN1ALDH1A1SMN1; SMN2GLAMAPT | |
| SCHEMBL2203014 | 0.85 | EGLN1 (0.74) | EGLN1ALDH1A1MAPTL3MBTL1TEAD4 | |
| SCHEMBL2204755 | 0.76 | EGLN1 (0.52) | EGLN1ALDH1A1 | |
| SCHEMBL2200760 | 0.72 | EGLN1 (1.00) | EGLN1ALDH1A1MAPT | |
| SCHEMBL7691046 | 0.72 | EGLN1 (0.53) | EGLN1ALDH1A1 | |
| SCHEMBL2206131 | 0.71 | EGLN1 (1.00) | EGLN1ALDH1A1 | |
| SCHEMBL2201947 | 0.71 | EGLN1 (0.79) | EGLN1ALDH1A1MAPT | |
| SCHEMBL12697382 | 0.71 | EGLN1 (0.79) | EGLN1ALDH1A1 | |
| SCHEMBL2204239 | 0.71 | EGLN1 (0.83) | EGLN1ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519503-A1 | SECONDARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES FOR USE AS ANTIFUNGAL AGENTS | POLICHEM S.A. (LU) | 2012-11-07 | — | — | EP | claimed |
| WO-2011080265-A1 | SECONDARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES FOR USE AS ANTIFUNGAL AGENTS | POLICHEM S.A. (LU) | 2011-07-07 | — | — | WO | claimed |