Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 9/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23523935 | 0.91 | S1PR1 (0.41) | S1PR1S1PR3KDM4EHPGDHSD17B10 | |
| SCHEMBL30355618 | 0.91 | S1PR1 (0.41) | S1PR1S1PR3KDM4EHPGDHSD17B10 | |
| SCHEMBL23524238 | 0.87 | NPC1 (0.44) | S1PR1S1PR3CA9HSD17B10NPC1 | |
| SCHEMBL23524204 | 0.85 | NPC1 (0.49) | S1PR1CA9KDM4EHPGDHSD17B10 | |
| SCHEMBL23558412 | 0.84 | TPH1 (0.42) | S1PR1S1PR3KDM4EHPGDHSD17B10 | |
| SCHEMBL30355766 | 0.81 | S1PR1 (0.53) | S1PR1S1PR3NPC1RAB9AMAPT | |
| SCHEMBL23524301 | 0.81 | S1PR1 (0.53) | S1PR1S1PR3NPC1RAB9AMAPT | |
| SCHEMBL23558493 | 0.80 | TPH1 (0.41) | S1PR1S1PR3KDM4EHSD17B10NPC1 | |
| SCHEMBL23558451 | 0.80 | NR1H4 (0.52) | S1PR1HPGDHSD17B10NPC1RAB9A | |
| SCHEMBL23558565 | 0.80 | NPC1 (0.42) | S1PR1S1PR3KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210188826-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | TREVENA, INC. | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188826-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | S1PR1, S1PR2, S1PR3 | S1PR1 1/4885S1PR3 3/4885ACACB 3779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.